885521-13-1 Usage
General Description
4-Methoxy-6-(1H)indazole carboxylic acid methyl ester is a chemical compound with the molecular formula C11H10N2O3. It is commonly used as an intermediate in the synthesis of pharmaceutical drugs and other organic compounds. 4-METHOXY-6-(1H)INDAZOLE CARBOXYLIC ACID METHYL ESTER is derived from indazole, which is a heterocyclic aromatic organic compound. The methoxy group attached to the indazole ring provides stability and can also affect the compound's reactivity and pharmacological properties. As a methyl ester, it can serve as a precursor to other ester compounds, and it may be used in the development of new medications or in research and development efforts in the chemical and pharmaceutical industries.
Check Digit Verification of cas no
The CAS Registry Mumber 885521-13-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,5,5,2 and 1 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 885521-13:
(8*8)+(7*8)+(6*5)+(5*5)+(4*2)+(3*1)+(2*1)+(1*3)=191
191 % 10 = 1
So 885521-13-1 is a valid CAS Registry Number.
885521-13-1Relevant articles and documents
Synthesis of unprotected carboxy indazoles via Pd-catalyzed carbonylation
Wainwright, Philip,Perni, Remedios,Vickers, Clare,Coffey, Steven B.,Buzon, Leanne,Dirico, Kenneth,Nelson, Kendra L.,Zhao, Zhengrong,Limberakis, Chris,Freeman-Cook, Kevin D.,Corbett, Jeffrey W.
experimental part, p. 1914 - 1921 (2012/06/18)
The first published synthesis of unprotected carboxy indazoles from the corresponding bromoindazoles is described. This is achieved via Pd(II)-catalyzed carbonylation and is demonstrated to work on a variety of indazoles.
SUBSTITUTED INDAZOLE AMIDES AND THEIR USE AS GLUCOKINASE ACTIVATORS
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Page/Page column 27-28, (2010/10/03)
The present invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof wherein R1, R4, R6, X, Y and Z are as defined herein. The compounds of Formula (I) have been found to act as glucokinase activators. Consequently, the compounds of Formula (I) and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucokinase.
