88559-47-1

Upstream product

• 54503-64-9 2,3-O-isopropylidene-5-O-trityl-D-ribofuranose 
• 3282-30-2 pivaloyl chloride 
• 84709-46-6 2,3-O-isopropylidene-5-O-(triphenylmethyl)-D-ribitol 

Downstream Products

• 88559-50-6 (4R,5S)-5-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-2-trityloxy-ethyl]-2,2-dimethyl-[1,3]dioxolane-4-carbaldehyde 
• 88559-56-2 (3aR,6aR)-2,2-dimethyl-6-[(trityloxy)methyl]-3a,6a-dihydro-4H-cyclopenta[d][1,3]dioxol-4-one 
• 88559-53-9 (2-{(4R,5S)-5-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-2-trityloxy-ethyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-2-oxo-ethyl)-phosphonic acid dimethyl ester 
• 88559-52-8 (2-{(4S,5S)-5-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-2-trityloxy-ethyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-2-hydroxy-ethyl)-phosphonic acid dimethyl ester 
• 88559-54-0 {2-[(4R,5R)-5-((R)-1-Hydroxy-2-trityloxy-ethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-2-oxo-ethyl}-phosphonic acid dimethyl ester 
• 88559-55-1 {2-[(4R,5S)-2,2-Dimethyl-5-(2-trityloxy-acetyl)-[1,3]dioxolan-4-yl]-2-oxo-ethyl}-phosphonic acid dimethyl ester 
• 88559-49-3 {(4S,5S)-5-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-2-trityloxy-ethyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-methanol 
• 88559-48-2 2,2-Dimethyl-propionic acid (4S,5S)-5-[(R)-1-(tert-butyl-dimethyl-silanyloxy)-2-trityloxy-ethyl]-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester 

Relevant academic research and scientific papers

A synthetic approach towards neplanocin A: Preparation of the optically active cyclopentene moiety from D-ribose

D (-)-ribose has been converted to the chiral 2-cyclopenten-1-one derivative 13 which has the correct stereochemistry and appropriate functionalities for the construction of neplanocin A.