885666-75-1Relevant academic research and scientific papers
A concise and efficient synthesis of spiroketals - Application to the synthesis of SPIKET-P and a spiroketal from bactrocera species
Tomas, Loic,Bourdon, Benjamin,Caille, Jean Claude,Gueyrard, David,Goekjian, Peter G.
, p. 915 - 920 (2013/03/28)
We report the synthesis of spiroketals by sequence of enol ether synthesis and cyclization. The enol ethers were prepared from lactones by a Julia olefination reaction, and the starting chiral lactone was prepared from an industrial intermediate. This route is a concise and efficient way to synthesize naturally occurring and biologically interesting spiroketals. We used this sequence for the preparation of SPIKET-P and a spiroketal from Bactrocera species. Copyright
Synthesis of γ- and δ-lactones from alkynols
Tiecco, Marcello,Testaferri, Lorenzo,Temperini, Andrea,Terlizzi, Raffaella,Bagnoli, Luana,Marini, Francesca,Santi, Claudio
, p. 587 - 590 (2007/10/03)
The reaction of alkynyl phenyl selenides with p-toluene-sulfonic acid gives rise to a proton-induced ring-closure reaction affording γ- and δ-lactones. Georg Thieme Verlag Stuttgart.
Microbiological transformations 60. Enantioconvergent baeyer-villiger oxidation via a combined whole cells and ionic exchange resin-catalysed dynamic kinetic resolution process
Gutierrez, Maria-Concepcion,Furstoss, Roland,Alphand, Veronique
, p. 1051 - 1059 (2007/10/03)
A dynamic kinetic resolution process was applied to an enantioconvergent microbial Baeyer-Villiger oxidation of benzyloxycyclopentanone, rac-1. This was achieved by combining a whole cell-based kinetic resolution and an anion exchange resin-catalysed in s
