885947-60-4Relevant academic research and scientific papers
Pd-NHC Catalytic System for the Efficient Atom-Economic Synthesis of Vinyl Sulfides from Tertiary, Secondary, or Primary Thiols
Degtyareva, Evgeniya S.,Burykina, Julia V.,Fakhrutdinov, Artem N.,Gordeev, Evgeniy G.,Khrustalev, Victor N.,Ananikov, Valentine P.
, p. 7208 - 7213 (2015)
Vinyl sulfides represent an important class of compounds in organic chemistry and materials science. Atom-economic addition of thiols to the triple bond of alkynes provides an excellent opportunity for environmentally friendly processes. We have found tha
Synthesis of vinyl sulfides via hydrothiolation of alkynes using Al2O3/KF under solvent-free conditions
Silva, Márcio S.,Lara, Renata G.,Marczewski, Júnior M.,Jacob, Raquel G.,Lenard?o, Eder J.,Perin, Gelson
, p. 1927 - 1930 (2008/09/19)
We present here a clean, solvent-free hydrothiolation of alkynes using solid supported catalyst (Al2O3/KF). This efficient and improved method selectively furnishes the corresponding anti-Markovnikov vinyl sulfides in good to excellent yields. The method is applicable for aliphatic and aromatic thiols and the catalytic system can be re-used up to two times without previous treatment and with comparable activity.
