88613-49-4Relevant academic research and scientific papers
A microwave-assisted synthesis of (S)-N-protected homoserine γ-lactones from l-aspartic acid
Singh, Suneel P.,Michaelides, Alex,Merrill, A. Rod,Schwan, Adrian L.
experimental part, p. 6825 - 6831 (2011/10/08)
A three-pot preparation of (S)-N-protected homoserine γ-lactones is presented. Conversion of N-protected l-aspartic acid to an oxazolidinone is followed by selective reduction/acid-catalyzed cyclization to deliver the lactones. Microwave irradiation proved valuable for improving the latter reaction steps in some cases.
