886193-82-4Relevant academic research and scientific papers
Selective monoarylation of acetate esters and aryl methyl ketones using aryl chlorides
Biscoe, Mark R.,Buchwald, Stephen L.
supporting information; experimental part, p. 1773 - 1775 (2009/09/06)
Simple, efficient procedures for the monoarylation of acetate esters and aryl methyl ketones using aryl chlorides are presented. Previously, no general method was available to ensure the highly selective monoarylation of these classes of substrates using
α-Heteroarylation of esters, lactones, amides, and lactams by nucleophilic aromatic substitution
Shen, Hong C.,Ding, Fa-Xiang,Colletti, Steven L.
, p. 1447 - 1450 (2007/10/03)
A mild and efficient α-heteroarylation of simple esters and amides was developed via nucleophilic aromatic substitution. The choice of NaHMDS in toluene gave the best results. A tandem α-heteroarylation and hydroxylation protocol using air as the oxidant
