88631-20-3Relevant academic research and scientific papers
Synthesis of L-Glutamic Acid Labelled Stereospecifically at C-3 with Deuterium and Non-stereospecifically at C-4 with Tritium
Field, Steven J.,Young, Douglas W.
, p. 2387 - 2392 (2007/10/02)
(2S,3S)-1>-, (2S,3R)-2>-, (2S,3S,4RS)-1,4-3H1>-, and (2S,3R,4RS)-2,4-3H1>-Glutamic acid have been synthesised from the corresponding labelled aspartic acids.The route involves a step where Wolff rearrangement occurs with retention of stereochemistry at a primary migrating chiral centre.The stereochemistry at C-3 of the glutamic acids has been verified by degradation to the corresponding stereospecifically labelled 1>succinic acids.
