886359-84-8

Basic information

• Product Name: (1R,2R,3R,6S)-4-hydroxy-4,7,7-trimethylbicyclo[4.1.0]hept-3-yl (2R)-2-fluoro-2-(4-phenoxyphenyl)propionate
• Synonyms: (1R,2R,3R,6S)-4-hydroxy-4,7,7-trimethylbicyclo[4.1.0]hept-3-yl (2R)-2-fluoro-2-(4-phenoxyphenyl)propionate
• CAS NO: 886359-84-8
• Molecular Weight: 412.501
• Mol File: 886359-84-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,2R,3R,6S)-4-hydroxy-4,7,7-trimethylbicyclo[4.1.0]hept-3-yl (2R)-2-fluoro-2-(4-phenoxyphenyl)propionate(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2R,3R,6S)-4-hydroxy-4,7,7-trimethylbicyclo[4.1.0]hept-3-yl (2R)-2-fluoro-2-(4-phenoxyphenyl)propionate(886359-84-8)
• EPA Substance Registry System: (1R,2R,3R,6S)-4-hydroxy-4,7,7-trimethylbicyclo[4.1.0]hept-3-yl (2R)-2-fluoro-2-(4-phenoxyphenyl)propionate(886359-84-8)

Safety Data

• Hazardous Substances Data: 886359-84-8(Hazardous Substances Data)

Upstream product

• 126934-95-0 methyl 2-(4-phenoxyphenyl)propionate 
• 3585-53-3 2-(4-phenoxyphenyl)propanoic acid 
• 863224-91-3 2-fluoro-2-(4-phenoxyphenyl)propionic acid 
• 863224-88-8 methyl 2-fluoro-2-(4-phenoxyphenyl)propionate 
• 22556-08-7 trans-3,4-caranediol 

Relevant articles and documents

Synthesis and optical resolution of 2-aryl-2-fluoropropionic acids, fluorinated analogues of Non-steroidal Anti-inflammatory Drugs (NSAIDs)

We report the synthesis of optically active 2-aryl-2-fluoropropionic acids 2 as non-epimerizable mimics of 2-arylpropionic acids 1, a class of compounds which have been widely used as non-steroidal anti-inflammatory drugs (NSAIDs). This is a continuation of our research involving the design, synthesis, and evaluation of chiral fluorine-containing organic molecules as effective analogues of pharmacologically important compounds.