886439-49-2Relevant academic research and scientific papers
The reactivity of related 6-amino- and 5,6-diaminouracils derived from 2-amino-5-(phenoxymethyl)-2-oxazoline: Efficient access to bicyclic pyrimidine derivatives
Massip, Stephane,Guillon, Jean,Sonnet, Pascal,Leger, Jean-Michel,Bosc, Jean-Jacques,Mueller, Christa E.,Jarry, Christian
, p. 2193 - 2197 (2007)
8-(Dimethylamino)-3-(2-hydroxy-3-phenoxypropyl)-xanthine has been obtained from 6-amino-1-(2-hydroxy-3-phenoxypropyl)uracil by an azodicarboxylate Michael-type addition involving a reactive diene. 6-Amino-1-(2-hydroxy-3- phenoxypropyl)uracil was easily pr
Synthesis and preliminary evaluation of new 1- and 3-[1-(2-hydroxy-3- phenoxypropyl)]xanthines from 2-amino-2-oxazolines as potential A1 and A2A adenosine receptor antagonists
Massip, Stephane,Guillon, Jean,Bertarelli, Daniela,Bosc, Jean-Jacques,Leger, Jean-Michel,Lacher, Svenja,Bontemps, Cecile,Dupont, Thibaut,Mueller, Christa E.,Jarry, Christian
, p. 2697 - 2719 (2007/10/03)
The development of potent and selective adenosine receptor ligands as potential drugs is an active area of research. Xanthines are one of the most important classes of adenosine receptor antagonists and have been widely developed in terms of affinity and
