886458-14-6Relevant academic research and scientific papers
Synthesis and anti-inflammatory activity of a series of N-substituted naproxen glycolamides: Nitric oxide-donor naproxen prodrugs
Ranatunge, Ramani R.,Augustyniak, Michael E.,Dhawan, Vijay,Ellis, James L.,Garvey, David S.,Janero, David R.,Letts, L. Gordon,Richardson, Stewart K.,Shumway, Mathew J.,Trocha, A. Mark,Young, Delano V.,Zemtseva, Irina S.
, p. 2589 - 2599 (2006)
A series of glycolamide naproxen prodrugs containing a nitrate group as a nitric oxide (NO) donor moiety has been synthesized. These compounds were evaluated for their anti-inflammatory activity, naproxen release, and gastric tolerance. Compounds 4a, 4b,
