886496-75-9 Usage
Uses
Used in Pharmaceutical Industry:
4-Chloro-2-(trifluoromethyl)benzyl bromide is used as a key intermediate in the synthesis of a novel series of dithiocarbamates. These dithiocarbamates are formed via the reaction of 4-chloro-2-(trifluoromethyl)benzyl bromide with sodium salts of N,N-disubstituted dithiocarbamic acids. The resulting dithiocarbamates hold potential applications in the development of new pharmaceutical agents, particularly in the area of medicinal chemistry.
Used in Organic Synthesis:
In the field of organic synthesis, 4-chloro-2-(trifluoromethyl)benzyl bromide serves as a valuable building block for the creation of various complex organic molecules. Its unique structural features, including the electron-withdrawing trifluoromethyl group and the electrophilic benzyl bromide, make it a useful component in the synthesis of a wide range of organic compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Research and Development:
4-Chloro-2-(trifluoromethyl)benzyl bromide is also utilized in research and development settings, where it can be employed to explore new reaction pathways, investigate the effects of structural modifications on chemical and biological properties, and develop new synthetic methodologies. Its reactivity and functional group compatibility make it a valuable tool for advancing the understanding of organic chemistry and its applications.
Check Digit Verification of cas no
The CAS Registry Mumber 886496-75-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,6,4,9 and 6 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 886496-75:
(8*8)+(7*8)+(6*6)+(5*4)+(4*9)+(3*6)+(2*7)+(1*5)=249
249 % 10 = 9
So 886496-75-9 is a valid CAS Registry Number.
886496-75-9Relevant academic research and scientific papers
DEUTERIUM ATOM-SUBSTITUTED INDOLE FORMAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL APPLICATIONS THEREOF
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Paragraph 0101; 0108; 0110; 0112, (2020/08/01)
A deuterium atom-substituted indole formamide derivative, a preparation method therefor, and medical applications thereof. Specifically, the present invention relates to a deuterium atom-substituted indole formamide derivative represented by general formula (I), a preparation method therefor, a pharmaceutical composition containing the derivative, and uses of the derivative serving as an ROR agonist and uses of the derivative in preventing and/or treating tumors or cancers, definitions of substituent groups in general formula (I) being same as definitions in the specification.
Hydrophilic group-substituted indole carboxamide derivative, preparation method thereof and application of hydrophilic group-substituted indole carboxamide derivative to medicine
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Paragraph 0230-0232; 0236-0238, (2019/04/09)
The invention relates to a hydrophilic group-substituted indole carboxamide derivative, a preparation method thereof and application of the hydrophilic group-substituted indole carboxamide derivativeto medicine, particularly to a hydrophilic group-substituted indole carboxamide derivative shown as the formula (I), a preparation method thereof and a drug composition comprising the hydrophilic group-substituted indole carboxamide derivative. Besides, the invention also relates to application of the hydrophilic group-substituted indole carboxamide derivative as an ROR (retinoid-related orphan receptors) agonist as well as to preventing and/or treating tumor or cancer. The substituent groups in the formula (1) are identical in definition in those in specifications.
