886496-75-9

Basic information

• Product Name: 4-CHLORO-2-(TRIFLUOROMETHYL)BENZYL BROMIDE
• Synonyms: 4-CHLORO-2-(TRIFLUOROMETHYL)BENZYL BROMIDE;4-chloro-2-(trifloromethyl)benzylbromide
• CAS NO: 886496-75-9
• Molecular Formula: C₈H₅BrClF₃
• Molecular Weight: 273.48
• Mol File: 886496-75-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 214.0±35.0 °C(Predicted)
• Appearance: /
• Density: 1.663±0.06 g/cm3(Predicted)
• Refractive Index: 1.5200
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility: Difficult to mix.
• CAS DataBase Reference: 4-CHLORO-2-(TRIFLUOROMETHYL)BENZYL BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLORO-2-(TRIFLUOROMETHYL)BENZYL BROMIDE(886496-75-9)
• EPA Substance Registry System: 4-CHLORO-2-(TRIFLUOROMETHYL)BENZYL BROMIDE(886496-75-9)

Safety Data

• RIDADR: UN3265
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 886496-75-9(Hazardous Substances Data)

Usage

Uses

4-Chloro-2-(trifluoromethyl)benzyl bromide is used in the synthesis of novel series of dithiocarbamates, via reaction with sodium salts of N,N-disubstituted dithiocarbamic acids

Upstream product

• 320-43-4 4-chloro-2-(trifluoromethyl)benzaldehyde 
• 773872-13-2 (4-chloro-2-(trifluoromethyl)phenyl)methanol 

Downstream Products

• 1312705-18-2 1-[4-chloro-2-(trifluoromethyl)-benzyl]-3-methyl-1H-indazol-5-carbaldehyde 
• 1351564-79-8 [(5Z)-5-({1-[4-chloro-2-(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]acetic acid 
• 1351565-70-2 2-[(5Z)-5-({1-[4-chloro-2-(trifluoromethyl)benzyl]-1Hindazol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]-N-(pyrrolidin-1-ylsulfonyl)acetamide 
• 1351567-63-9 N-({[(5Z)-5-({1-[4-chloro-2-(trifluoromethyl)benzyl]-1Hindazol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]methyl} sulfonyl)acetamide 
• 1351565-32-6 2-[(5Z)-5-({1-[4-chloro-2-(trifluoromethyl)benzyl]-1Hindazol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]-N-sulfamoylacetamide 
• 1351566-92-1 (5Z)-5-({1-[4-chloro-2-(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-3-(2-pyrrolidin-1-ylethyl)-1,3-thiazolidine-2,4-dione 
• 1351567-03-7 (5Z)-5-({1-[4-chloro-2-(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-3-{[(2S)-1-methylpyrrolidin-2-yl]methyl}-1,3-thiazolidine-2,4-dione 
• 1351564-75-4 (5Z)-5-({1-[4-Chloro-2-(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-3-{2-[(3S)-3-hydroxypyrrolidin-1-yl]ethyl}-1,3-thiazolidine-2,4-dione 
• 1351564-76-5 (5Z)-5-({1-[4-chloro-2-(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidine 
• 1351564-78-7 (5Z)-5-({1-[4-chloro-2-(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-3-(2-morpholin-4-ylethyl)-1,3-thiazolidine-2,4-dione 
• 1351565-62-2 2-[(5Z)-5-({1-[4-chloro-2-(trifluoromethyl)benzyl]-1Hindazol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]-N-(dimethylsulfamoyl)acetamide 
• 1351565-63-3 [(5Z)-5-({1-[4-chloro-2-(trifluoromethyl)benzyl]-3-methyl-1H-indazol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]aceticacid 
• 1351565-72-4 2-[(5Z)-5-({1-[4-chloro-2-(trifluoromethyl)benzyl]-3-methyl-1H-indazol-5-yl}methylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]-N-(pyrrolidin-1-ylsulfonyl)acetamide 
• 1351565-81-5 (5Z)-5-({1-[4-Chloro-2-(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-3-[2-(ethylamino)ethyl]-1,3-thiazolidine-2,4-dione 

Relevant articles and documents

DEUTERIUM ATOM-SUBSTITUTED INDOLE FORMAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL APPLICATIONS THEREOF

A deuterium atom-substituted indole formamide derivative, a preparation method therefor, and medical applications thereof. Specifically, the present invention relates to a deuterium atom-substituted indole formamide derivative represented by general formula (I), a preparation method therefor, a pharmaceutical composition containing the derivative, and uses of the derivative serving as an ROR agonist and uses of the derivative in preventing and/or treating tumors or cancers, definitions of substituent groups in general formula (I) being same as definitions in the specification.