886594-59-8Relevant academic research and scientific papers
A concise and selective synthesis of novel 5-aryloxyimidazole NNRTIs
Jones, Lyn H.,Dupont, Thomas,Mowbray, Charles E.,Newman, Sandra D.
, p. 1725 - 1727 (2007/10/03)
A concise and efficient route to the construction of a 5-aryloxyimidazole has been developed. The key step was the selective O-arylation of a 2,4-dimethoxybenzyl-protected imidazolone. The final compound is a potent inhibitor of HIV reverse transcriptase.
