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Usage

Uses

Used in Pharmaceutical Industry:
1-BOC-3-O-TOLYLPIPERAZINE is used as a chemical intermediate for the synthesis of various drugs, leveraging its structural properties to contribute to the development of new medications.
Used in Drug Development:
As a compound with potential biological activity, 1-BOC-3-O-TOLYLPIPERAZINE is utilized in research for its possible applications in creating pharmaceuticals with specific therapeutic effects.
Used in Research:
1-BOC-3-O-TOLYLPIPERAZINE is employed in scientific studies to explore its properties and understand its role in the synthesis of active pharmaceutical ingredients, potentially leading to advancements in medicinal chemistry.

Upstream product

• 1557287-99-6 tert-butyl (2-aminoethyl)((tributylstannyl)methyl)carbamate 
• 529-20-4 2-methylphenyl aldehyde 
• 57260-73-8 N-BOC-1,2-diaminoethane 

Relevant academic research and scientific papers

Catalytic Synthesis of N-Unprotected Piperazines, Morpholines, and Thiomorpholines from Aldehydes and SnAP Reagents

Commercially available SnAP (stannyl amine protocol) reagents allow the transformation of aldehydes and ketones into a variety of N-unprotected heterocycles. By identifying new ligands and reaction conditions, a robust catalytic variant that expands the substrate scope to previously inaccessible heteroaromatic substrates and new substitution patterns was realized. It also establishes the basis for a catalytic enantioselective process through the use of chiral ligands. SnAPcat! The identification of new ligands and reaction conditions provides a robust catalytic method for the synthesis of N-unprotected heterocycles using SnAP reagents. This catalytic variant expands the substrate scope to include previously inaccessible piperazines, morpholines, and thiomorpholines and establishes the basis for a catalytic enantioselective process through the use of chiral ligands.