886855-44-3

Basic information

• Product Name: 4-(6-bromo-imidazo[1,2-a]pyrazin-8-ylamino)-benzonitrile
• Synonyms: 4-(6-bromo-imidazo[1,2-a]pyrazin-8-ylamino)-benzonitrile
• CAS NO: 886855-44-3
• Molecular Weight: 314.144
• Mol File: 886855-44-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(6-bromo-imidazo[1,2-a]pyrazin-8-ylamino)-benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(6-bromo-imidazo[1,2-a]pyrazin-8-ylamino)-benzonitrile(886855-44-3)
• EPA Substance Registry System: 4-(6-bromo-imidazo[1,2-a]pyrazin-8-ylamino)-benzonitrile(886855-44-3)

Safety Data

• Hazardous Substances Data: 886855-44-3(Hazardous Substances Data)

Upstream product

• 63744-22-9 6,8-dibromoimidazo[1,2-a]pyrazine 
• 873-74-5 4-Aminobenzonitrile 

Downstream Products

• 886855-45-4 4-[6-(3-amino-2-methyl-phenyl)-imidazo[1,2-a]pyrazin-8-ylamino]-benzonitrile 
• 886855-47-6 4-{6-[3-(4-tert-butyl-benzoylamino)-2-methyl-phenyl]-imidazo[1,2-a]pyrazin-8-ylamino}-benzimidic acid ethyl ester hydrochloride 
• 886855-54-5 4-tert-butyl-N-(3-{8-[4-(4,5-dihydro-1H-imidazol-2-yl)-phenylamino]-imidazo[1,2-a]pyrazin-6-yl}-2-methyl-phenyl)-benzamide 
• 886855-43-2 4-tert-butyl-N-(2-methyl-3-{8-[4-(N-methylcarbamimidoyl)-phenylamino]-imidazo[1,2-a]pyrazin-6-yl}-phenyl)-benzamide 
• 886855-53-4 4-tert-butyl-N-(3-{8-[4-(N,N'-dimethyl-carbamimidoyl)-phenylamino]-imidazo[1,2-a]pyrazin-6-yl}-2-methyl-phenyl)-benzamide 
• 886855-46-5 4-tert-butyl-N-{3-[8-(4-cyano-phenylamino)-imidazo[1,2-a]pyrazin-6-yl]-2-methyl-phenyl}-benzamide 

Relevant articles and documents

KINASE INHIBITORS, AND METHODS OF USING AND IDENTIFYING KINASE INHIBITORS

Methods of inhibiting BTK activity by inhibiting phosphorylation of Y551 of BTK, methods of treating patients by inhibiting BTK activity by inhibiting phosphorylation of Y551 of BTK, chemical entities that bind to BTK and inhibited complexes are provided.