886861-59-2Relevant academic research and scientific papers
A novel series of arylsulfonylthiophene-2-carboxamidine inhibitors of the complement component C1s
Subasinghe, Nalin L.,Travins, Jeremy M.,Ali, Farah,Huang, Hui,Ballentine, Shelley K.,Marugan, Juan Jose,Khalil, Ehab,Hufnagel, Heather R.,Bone, Roger F.,Desjarlais, Renee L.,Crysler, Carl S.,Ninan, Nisha,Cummings, Maxwell D.,Molloy, Christopher J.,Tomczuk, Bruce E.
, p. 2200 - 2204 (2007/10/03)
Inhibiting the classical pathway of complement activation by attenuating the proteolytic activity of the serine protease C1s is a potential strategy for the therapeutic intervention in disease states such as hereditary angioedema, ischemia-reperfusion inj
