887113-28-2

Upstream product

• 887113-27-1 (S)-2-phenyl-1-tosyl-2,5-dihydro-1H-pyrrole 
• 168126-70-3 (S)-4-methyl-N-(1-phenylallyl)benzenesulfonamide 
• 887113-26-0 N-allyl-4-methyl-N-(1-phenyl-allyl)-benzenesulfonamide 
• 887113-32-8 4-methyl-N-(2-oxo-1-phenyl-ethyl)-benzenesulfonamide 

Downstream Products

• 474558-83-3 (2R,3R,4S)-(-)-N-tert-butoxycarbonyl-3,4-dihydroxy-2-phenyl-pyrrolidine isopropylidene acetal 
• 887113-29-3 (3aR,4R,6aS)-2,2-Dimethyl-4-phenyl-5-(toluene-4-sulfonyl)-tetrahydro-[1,3]dioxolo[4,5-c]pyrrole 

Relevant academic research and scientific papers

Asymmetric synthesis of α-amino aldehydes from sulfinimine (N-sulfinyl imine)-derived α-amino 1,3-dithianes. Formal synthesis of (-)-2,3-trans-3,4-cis-dihydroxyproline

Hydrolysis of sulfinimine-derived N-sulfinyl α-amino 1,3-dithianes with aqueous 1,3-dibromo-5,5-dimethylhydantoin affords the corresponding N-tosyl α-amino aldehydes in good yield and high enantiomeric purity. These aldehydes can be reduced to amino alcoh