887232-72-6Relevant articles and documents
Synthesis and biological evaluation of cyclopropyl analogues of fosmidomycin as potent Plasmodium falciparum growth inhibitors
Devreux, Vincent,Wiesner, Jochen,Goeman, Jan L.,Van Der Eycken, Johan,Jomaa, Hassan,Van Calenbergh, Serge
, p. 2656 - 2660 (2007/10/03)
A series of fosmidomycin analogues featuring restricted conformational mobility has been synthesized and evaluated as inhibitors of 1-deoxy-D-xylulose 5-phosphate (DOXP) reductoisomerase and as growth inhibitors of P. falciparum. The enantiomerically pure