887232-76-0Relevant academic research and scientific papers
Synthesis and biological evaluation of cyclopropyl analogues of fosmidomycin as potent Plasmodium falciparum growth inhibitors
Devreux, Vincent,Wiesner, Jochen,Goeman, Jan L.,Van Der Eycken, Johan,Jomaa, Hassan,Van Calenbergh, Serge
, p. 2656 - 2660 (2007/10/03)
A series of fosmidomycin analogues featuring restricted conformational mobility has been synthesized and evaluated as inhibitors of 1-deoxy-D-xylulose 5-phosphate (DOXP) reductoisomerase and as growth inhibitors of P. falciparum. The enantiomerically pure
