887245-02-5

Basic information

• Product Name: 2,2-bis(4'-[N-(tert-butoxycarbonyl)amino]phenyl)-5,5-bi-1H-benzimidazole
• Synonyms: 2,2-bis(4'-[N-(tert-butoxycarbonyl)amino]phenyl)-5,5-bi-1H-benzimidazole
• CAS NO: 887245-02-5
• Molecular Weight: 616.72
• Mol File: 887245-02-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,2-bis(4'-[N-(tert-butoxycarbonyl)amino]phenyl)-5,5-bi-1H-benzimidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-bis(4'-[N-(tert-butoxycarbonyl)amino]phenyl)-5,5-bi-1H-benzimidazole(887245-02-5)
• EPA Substance Registry System: 2,2-bis(4'-[N-(tert-butoxycarbonyl)amino]phenyl)-5,5-bi-1H-benzimidazole(887245-02-5)

Safety Data

• Hazardous Substances Data: 887245-02-5(Hazardous Substances Data)

Upstream product

• 144072-29-7 tert-butyl N-[4-(hydroxymethyl)phenyl]carbamate 
• 623-04-1 4-aminobenzenemethanol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 144072-30-0 4-((tert-butoxycarbonyl)amino)benzaldehyde 
• 7411-49-6 3,3',4,4'-tetraaminobiphenyl tetrahydrochloride dihydrate 

Downstream Products

• 887245-04-7 2,2-bis-(4'-[3''-chloropropanamido]phenyl)-5,5-bi-1H-benzimidazole 
• 4402-17-9 4,4'-(1H,1'H-[5,5'-bibenzo[d]imidazole]-2,2'-diyl)dianiline 

Relevant articles and documents

New mustard-linked 2-aryl-bis-benzimidazoles with anti-proliferative activity

We describe new methodology for the synthesis of symmetric bis-benzimidazoles carrying 2-aryl moieties, including 2-[4-(3′- aminopropoxy)phenyl] and 2-[4-(3′-aminopropanamido)phenyl] substituents, together with the synthesis of novel hybrid molecules comprising bis-benzimidazoles in ester and amide combination with the N-mustard chlorambucil. The in vitro activities of these compounds against five cancer cell lines are also provided. The Royal Society of Chemistry 2006.