887330-22-5Relevant academic research and scientific papers
First total synthesis of longimicin D
Tominaga, Hiroaki,Maezaki, Naoyoshi,Yanai, Minori,Kojima, Naoto,Urabe, Daisuke,Ueki, Risa,Tanaka, Tetsuaki
, p. 1422 - 1429 (2007/10/03)
We have accomplished the first total synthesis of longimicin D (1), which displays potent cytotoxicity against human pancreatic carcinoma cells. The bis-THF core bearing congested stereocenters was constructed by our methodology for synthesis of poly-THF
