887330-29-2

Upstream product

• 532384-82-0 (2R,5R,6R,9R,10R)-10-(tert-butyldimethylsilyloxy)-2,5;6,9-diepoxy-1-docosanol 
• 106673-33-0 8-benzyloxy-1-octanal 
• 887330-26-9 (8R,11R,12R,15R,16R,19R,20R)-1-(benzyloxy)-20-(tert-butyldimethylsilyloxy)-12,15:16,19-diepoxy-8,11-bis(methoxymethoxy)dotriacont-9-yne 
• 887330-25-8 (1R,4R)-11-(benzyloxy)-1-[(1R,4R,5R,8R,9R)-9-(tert-butyldimethylsilyloxy)-1,4:5,8-diepoxyhenycosanyl]-4-(methoxymethoxy)undec-2-yn-1-ol 
• 887330-27-0 (8R,11R,12R,15R,16R,19R,20R)-20-(tert-butyldimethylsilyloxy)-12,15:16,19-diepoxy-8,11-bis(methoxymethoxy)dotriacontan-1-ol 
• 887330-24-7 (2R,5R,2'R,5'R)-5'-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-tridecyl]-octahydro-[2,2']bifuranyl-5-carbaldehyde 
• 929915-18-4 10-benzyloxy-1-trimethylsilanyl-dec-1-yn-3-ol 
• 887330-22-5 (3R)-10-(benzyloxy)-3-(methoxymethoxy)dec-1-yne 
• 887330-30-5 (3R)-10-(benzyloxy)dec-1-yn-3-ol 
• 887330-19-0 rac-10-(benzyloxy)dec-1-yn-3-ol 
• 887330-20-3 10-(benzyloxy)dec-1-yn-3-one 
• 887330-28-1 (8R,11R,12R,15R,16R,19R,20R)-20-(tert-butyldimethylsilyloxy)-12,15:16,19-diepoxy-1-iodo-8,11-bis(methoxymethoxy)dotriacontane 
• 184435-75-4 (5S)-5-methyl-3-phenylsulfanyl-4,5-dihydrofuran-2(3H)-one 

Relevant academic research and scientific papers

First total synthesis of longimicin D

We have accomplished the first total synthesis of longimicin D (1), which displays potent cytotoxicity against human pancreatic carcinoma cells. The bis-THF core bearing congested stereocenters was constructed by our methodology for synthesis of poly-THF