887616-87-7Relevant academic research and scientific papers
Direct nucleophilic acylation of nitroalkenes promoted by a fluoride anion/thiourea combination
Mattson, Anita E.,Zuhl, Andrea M.,Reynolds, Troy E.,Scheldt, Karl A.
, p. 4932 - 4933 (2006)
The direct nucleophilic acylation of nitroalkenes is reported utilizing a fluoride-initiated rearrangement of protected thiazolium carbinols. The key combination of fluoride anion and thiourea accesses carbonyl anion reactivity without the use of amine or
NHC-Stabilized Radicals in the Formal Hydroacylation Reaction of Alkynes
Phan, Jenny,Ruser, Stephanie-M.,Zeitler, Kirsten,Rehbein, Julia
supporting information, p. 557 - 561 (2018/11/23)
Mechanistic details of transformations catalyzed by N-heterocyclic carbenes (NHC) are currently of great interest, targeting questions on the active catalyst in operation and the structure and reactivity of key intermediates. These mechanistic studies are
The NHCs-mediated cross-coupling of aromatic aldehydes with benzyl halides: Synthesis of α-aryl ketones
Lin, Lu,Li, Yi,Du, Wenting,Deng, Wei-Ping
scheme or table, p. 3571 - 3574 (2010/08/07)
A new NHCs-mediated synthetic method was found to produce α-aryl ketones in 22-63% yields in one-pot process from the corresponding aromatic aldehydes and benzyl halides. This method is the first example of the NHCs-mediated intermolecular nucleophilic acylation of aromatic aldehydes with benzyl halides.
