887747-71-9Relevant academic research and scientific papers
Neighbouring group participation vs. addition to oxacarbenium ions: Studies on the synthesis of mycobacterial oligosaccharides
Stalford, Susanne A.,Kilner, Colin A.,Leach, Andrew G.,Turnbull, W. Bruce
experimental part, p. 4842 - 4852 (2010/02/16)
Neighbouring group participation is frequently used to control the stereoselectivity of chemical reactions. Herein, we investigate the use of neighbouring group participation for the synthesis of disaccharides incorporating the mycobacterial sugar methylt
IMMUNOMODULATORY SACCHARIDE COMPOUNDS
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Page/Page column 12, (2010/11/28)
Compounds comprising a saccharide molecule and a 5-deoxy-5-methylthio-xylofuranose (MTX) moiety or a 5-deoxy-5-methylsulfoxy-xylofuranose (MSX) moiety, and use of such compounds in methods for modulating inflammation and immune responses.
The 5-deoxy-5-methylthio-xylofuranose residue in mycobacterial lipoarabinomannan. Absolute stereochemistry, linkage position, conformation, and immunomodulatory activity
Joe, Maju,Sun, Daniel,Taha, Hashem,Completo, Gladys C.,Croudace, Joanne E.,Lammas, David A.,Besra, Gurdyal S.,Lowary, Todd L.
, p. 5059 - 5072 (2007/10/03)
Mycobacteria produce a cell-surface glycoconjugate, lipoarabinomannan (LAM), which has been shown to be a potent modulator of the immune response that arises from infection by these organisms. Recently, LAM from the human pathogens Mycobacterium tuberculo
