88776-67-4

Upstream product

• 96-09-3 styrene oxide 
• 42973-53-5 2-methoxy-4-((methylamino)methyl)phenol 
• 128942-55-2 N-(4-hydroxy-3-methoxybenzyl)-N-methylaminoacetophenone 
• 128942-61-0 4-{[(2-Hydroxy-2-phenyl-ethyl)-methyl-amino]-methyl}-2-methoxy-phenol 
• 88741-49-5 (4-benzyloxy-3-methoxy-benzyl)-methyl-amine 
• 88741-45-1 2-[(4-Benzyloxy-3-methoxy-benzyl)-methyl-amino]-1-phenyl-ethanol 
• 121-33-5 vanillin 

Relevant academic research and scientific papers

A New Synthesis of 1,2,3,4-Tetrahydro-2-methyl-4-phenylisoquinolines

1,2,3,4-Tetrahydro-2-methyl-4-phenylisoquinolines 6 are obtained from aromatic aldehydes 1, methyl amine and α-haloacetophenones 2 in the presence of sodium borohydride followed by cyclization with sulfuric acid and zinc in methanol.

A FACILE SYNTHESIS OF 4-ARYL-1,2,3,4-TETRAHYDROISOQUINOLINES: A TOTAL SYNTHESIS OF (+/-)-CHERYLLINE

Reaction of benzylamines (3a-d) and styrene oxide at 140 deg C gave quantitavely β-hydroxyphenethylamine (2a-d), acid treatment of which afforded 4-aryl-1,2,3,4-tetrahydroisoquinolines (8a-d) in high yields.On the other hand, the styrene oxide (10 or 15)