887904-37-2Relevant academic research and scientific papers
Synthesis and biological evaluation of B-ring modified colchicine and isocolchicine analogs
Cifuentes, Michael,Schilling, Brett,Ravindra, Rudravajhala,Winter, Jacquelyn,Janik, Mark E.
, p. 2761 - 2764 (2007/10/03)
A series of modified colchicine and isocolchicine analogs (C-7 substituent) were synthesized and evaluated in vitro against a PC3 cancer cell line and for inhibition of microtubule polymerization. The colchicine analogs all displayed strong inhibition of
