887922-04-5

Basic information

• Product Name: (8R)-2-phenyl-8-benzoyloxy-5,6,7,8-tetrahydroquinoline
• Synonyms: (8R)-2-phenyl-8-benzoyloxy-5,6,7,8-tetrahydroquinoline
• CAS NO: 887922-04-5
• Molecular Weight: 329.398
• Mol File: 887922-04-5.mol

Chemical Properties

• CAS DataBase Reference: (8R)-2-phenyl-8-benzoyloxy-5,6,7,8-tetrahydroquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: (8R)-2-phenyl-8-benzoyloxy-5,6,7,8-tetrahydroquinoline(887922-04-5)
• EPA Substance Registry System: (8R)-2-phenyl-8-benzoyloxy-5,6,7,8-tetrahydroquinoline(887922-04-5)

Safety Data

• Hazardous Substances Data: 887922-04-5(Hazardous Substances Data)

Upstream product

• 92850-41-4 8-hydroxy-2-phenyl-5,6,7,8-tetrahydroquinoline 
• 98-88-4 benzoyl chloride 
• 1570-04-3 2-phenyl-5,6,7,8-tetrahydroquinoline 
• 92850-39-0 2-phenyl-5,6,7,8-tetrahydroquinoline N-oxide 

Downstream Products

• 887922-07-8 (R)-8-hydroxy-2-phenyl-5, 6, 7, 8-tetrahydroquinoline 

Relevant articles and documents

Kinetic resolution of diols and pyridyl alcohols by cu(II)(borabox)- catalyzed acylation

Boron-bridged bisoxazoline (borabox) ligands have been used in the copper(II)-catalyzed benzoylation of pyridyl alcohols and 1,2-diols. Efficient kinetic resolution of 1,2-diols was achieved using both borabox and bisoxazoline (box) ligands. Borabox ligands induced high selectivities in the benzoylation of suitable pyridyl alcohols, where they outperformed bisoxazolines. In addition, highly enantioselective Cu(II)(borabox)-catalyzed benzoylation has been used for the synthesis of both enantiomers of a pyridyl alcohol.

Kinetic resolution of pyridyl alcohols by Cu(II)(borabox)-catalyzed acylation

Kinetic resolution of pyridyl alcohols has been achieved using copper(II)(borabox)-catalyzed benzoylation. Selectivity factors (k rel) of up to 125 have been observed and application to the synthesis of chiral pyridyl phosphine ligands is descr