887922-92-1 Usage
General Description
4-ISOCYANATO-1-METHYL-1H-INDOLE is a chemical compound with the formula C10H8N2O. It is an isocyanate derivative with a methyl and indole group, and is commonly used in the synthesis of pharmaceuticals, agrochemicals, and dyes. Isocyanates are highly reactive and are known to cause skin and respiratory sensitization, irritation, and even allergic reactions if not handled properly. Therefore, strict safety precautions and proper handling are necessary when working with this chemical. It is important to use appropriate protective equipment and work in a well-ventilated area when dealing with 4-ISOCYANATO-1-METHYL-1H-INDOLE to avoid any potential health hazards.
Check Digit Verification of cas no
The CAS Registry Mumber 887922-92-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,7,9,2 and 2 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 887922-92:
(8*8)+(7*8)+(6*7)+(5*9)+(4*2)+(3*2)+(2*9)+(1*2)=241
241 % 10 = 1
So 887922-92-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H8N2O/c1-12-6-5-8-9(11-7-13)3-2-4-10(8)12/h2-6H,1H3
887922-92-1Relevant articles and documents
Synthesis of highly substituted indole alkaloid species via [4+1] cyclization of nucleophilic carbenes and indole isocyanates
Rigby, James H.,Burke, Patrick J.
, p. 643 - 653 (2006)
Thermally induced [4+1] cyclization between indole isocyanates and dimethoxycarbene or bis(propylthio)carbene has been achieved with good chemical efficiency. The methodology provides rapid access to fused pyrroloindole substructures commonly found in a variety of indole alkaloid natural products.
