888028-36-2

Usage

Uses

Used in Pharmaceutical Research and Drug Development:
(1S)-1-amino-1-(4-fluorophenyl)-2-methylpropan-2-ol serves as a chiral building block in the synthesis of various biologically active compounds. Its unique molecular structure allows for the creation of enantiomer-specific drugs, which can have different pharmacological effects and reduce potential side effects.
Used in Medicinal Chemistry and Drug Design:
In the field of medicinal chemistry, (1S)-1-amino-1-(4-fluorophenyl)-2-methylpropan-2-ol is utilized for the development of new drug candidates with improved pharmacological properties. Its enantiomeric nature enables the design of more effective and safer medications by targeting specific biological pathways and minimizing off-target interactions.

Upstream product

• 916602-09-0 (S)-methyl 2-amino-2-(4-fluorophenyl)acetate hydrochloride 
• 75-16-1 methylmagnesium bromide 
• 42718-18-3 methyl (2S)-amino(4-fluorophenyl)ethanoate hydrochloride 
• 170902-74-6 (S)-methyl 2-amino-2-(4-fluorophenyl)acetate 
• 19883-57-9 (S)-2-amino-2-(4-fluorophenyl)acetic acid 

Downstream Products

• 1456504-76-9 (S)-4-(4-(4-fluorophenyl)-5,5-dimethyl-2-oxooxazolidin-3-yl)-N-(quinolin-8-yl)benzamide 
• 1456506-82-3 (S)-4-(4-fluorophenyl)-5,5-dimethyloxazolidin-2-one 

Relevant academic research and scientific papers

SUBSTITUTED PYRAZINE CARBOXAMIDE DERIVATIVES AS PROSTAGLANDIN EP3 RECEPTOR ANTAGONISTS

The invention relates to substituted pyrazine carboxamide derivatives of formula (I) and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/ or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and diabetes, and also urogenital and ophthalmic disorders.

SUBSTITUTED IMIDAZO PYRIMIDINE EP3 ANTAGONISTS

The invention relates to substituted imidazo pyrimidine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferabl

SUBSTITUTED PYRROLO TRIAZINE CARBOXAMIDE DERIVATIVES AS PROSTAGLANDIN EP3 RECEPTOR ANTAGONISTS

The invention relates to substituted pyrrole triazine carboxamide derivatives of formula (I) and to processes for their preparation, and also /to their use for preparing medicaments for the treatment and/ or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and diabetes, and also urogenital and ophthalmic disorders.

SUBSTITUTED DIHYDROPYRAZOLO PYRAZINE CARBOXAMIDE DERIVATIVES

The invention relates to substituted dihydropyrazolo pyrazine carboxamide derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular disorders, preferably thrombotic or thromboembolic disorders, and diabetes, and also urogenital and ophthalmic disorders.

OXAZOLIDINONE COMPOUNDS AND DERIVATIVES THEREOF

Compounds of Formula (I) and Formula (II) are useful inhibitors of tankyrase. Compounds of Formula (I) and Formula (II) have the following structure: where the definitions of the variables are provided herein.