88812-69-5

Basic information

• Product Name: 3-Isoxazolamine, N-[(4-methoxyphenyl)methylene]-5-methyl-
• CAS NO: 88812-69-5
• Molecular Formula: C12H12N2O2
• Molecular Weight: 216.239
• Mol File: 88812-69-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 3-Isoxazolamine, N-[(4-methoxyphenyl)methylene]-5-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Isoxazolamine, N-[(4-methoxyphenyl)methylene]-5-methyl-(88812-69-5)
• EPA Substance Registry System: 3-Isoxazolamine, N-[(4-methoxyphenyl)methylene]-5-methyl-(88812-69-5)

Safety Data

• Hazardous Substances Data: 88812-69-5(Hazardous Substances Data)

Upstream product

• 1072-67-9 5-methylisoxazol-3-ylamine 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 1269531-10-3 N-(4-methoxybenzyl)-N-(5-methyl-3-isoxazolyl)-amine 
• 1206182-23-1 5-(6-methoxynaphthalen-2-yl)-1-(4-methoxyphenyl)-1-(5-methylisoxazol-3-ylamino)pentan-3-one 
• 1295478-31-7 C₂₀H₁₇ClN₄O₃S 
• 1295478-19-1 C₂₀H₁₈N₄O₃S 
• 1295478-05-5 C₁₃H₁₃N₃O₂S 
• 119485-43-7 1,3-Bis-(4-methoxy-phenyl)-2-(5-methyl-isoxazol-3-yl)-2,3-dihydro-1H-naphtho[1,2-e][1,3]oxazine 
• 119485-34-6 1-[(4-methoxy-phenyl)-(5-methyl-isoxazol-3-ylamino)-methyl]-naphthalen-2-ol 

Relevant articles and documents

Features of 3-amino-5-methylisoxazole in heterocyclizations involving pyruvic acids

[Figure not available: see fulltext.] The chemical properties of 3-amino-5-methylisoxazole in the reactions involving pyruvic acid derivatives are reported. The multicomponent condensation of 3-amino-5-methylisoxazole, aromatic aldehyde, and pyruvic acid was not effective while the treatment of the starting amine with pyruvic acid derivatives led to suitable synthetic procedures for selective synthesis of furanones and pyrrolones. It was established that only NH2-nucleophilic center of 3-amino-5-methylisoxazole takes part in the heterocyclizations with pyruvic acid derivatives.

Synthesis and antidiabetic performance of β-amino ketone containing nabumetone moiety

We wish to report the further design and improved synthesis that resulted in two series of target molecules, TM-1 and TM-2, with remarkably simplified structures containing β-amino ketone of discrete nabumetone moiety. These were obtained via a 'one-pot,

Synthesis of isoxazolyl oxadiazolines and thiazolidinones

4-(5-Methyl-3-isoxazolyl)-3,5-diaryl-Δ2-1,2,4-oxadiazolines have been prepared by benzonitrile oxide addition to 3-benzalamino-5-methyl isoxazoles. The Schiff bases have been obtained by the condensation of aromatic aldehydes with 3-amino-5-met