88812-69-5

Upstream product

• 1072-67-9 5-methylisoxazol-3-ylamine 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 119485-43-7 1,3-Bis-(4-methoxy-phenyl)-2-(5-methyl-isoxazol-3-yl)-2,3-dihydro-1H-naphtho[1,2-e][1,3]oxazine 
• 119485-34-6 1-[(4-methoxy-phenyl)-(5-methyl-isoxazol-3-ylamino)-methyl]-naphthalen-2-ol 
• 1295478-05-5 C₁₃H₁₃N₃O₂S 
• 1295478-19-1 C₂₀H₁₈N₄O₃S 
• 1295478-31-7 C₂₀H₁₇ClN₄O₃S 
• 1269531-10-3 N-(4-methoxybenzyl)-N-(5-methyl-3-isoxazolyl)-amine 
• 1206182-23-1 5-(6-methoxynaphthalen-2-yl)-1-(4-methoxyphenyl)-1-(5-methylisoxazol-3-ylamino)pentan-3-one 

Relevant academic research and scientific papers

Features of 3-amino-5-methylisoxazole in heterocyclizations involving pyruvic acids

[Figure not available: see fulltext.] The chemical properties of 3-amino-5-methylisoxazole in the reactions involving pyruvic acid derivatives are reported. The multicomponent condensation of 3-amino-5-methylisoxazole, aromatic aldehyde, and pyruvic acid was not effective while the treatment of the starting amine with pyruvic acid derivatives led to suitable synthetic procedures for selective synthesis of furanones and pyrrolones. It was established that only NH2-nucleophilic center of 3-amino-5-methylisoxazole takes part in the heterocyclizations with pyruvic acid derivatives.

Unusual products of reaction between aminoisoxazoles and aromatic aldehydes

The reaction between primary amine and aldehyde usually leads to a Schiff base. In this work, we present the results of research (NMR, ATR-FTIR, UV–Vis, and X-ray) of products obtained in the reaction of 5-methyl-3-aminoisoxazole (3AMI) or 3-methyl-5-amin

Synthesis and antidiabetic performance of β-amino ketone containing nabumetone moiety

We wish to report the further design and improved synthesis that resulted in two series of target molecules, TM-1 and TM-2, with remarkably simplified structures containing β-amino ketone of discrete nabumetone moiety. These were obtained via a 'one-pot,

A fast and highly efficient protocol for reductive amination of aromatic aldehydes using NaBH4 and isoxazole amines in an ionic liquid medium

Reductive amination of aromatic aldehydes using NaBH4 and isoxazole amines is carried out in a Bronsted acidic ionic liquid 1-methylimidazolium tetrafluoroborate [(HMIm)BF4]. The ionic liquid plays dual roles of solvent as well as ca

Synthesis of isoxazolyl oxadiazolines and thiazolidinones

4-(5-Methyl-3-isoxazolyl)-3,5-diaryl-Δ2-1,2,4-oxadiazolines have been prepared by benzonitrile oxide addition to 3-benzalamino-5-methyl isoxazoles. The Schiff bases have been obtained by the condensation of aromatic aldehydes with 3-amino-5-met