88829-98-5Relevant articles and documents
Rhodium-catalyzed hydroformylation of alkynes employing a self-assembling ligand system
Agabekov, Vladislav,Seiche, Wolfgang,Breit, Bernhard
, p. 2418 - 2422 (2013)
Hydroformylation of alkynes is an underdeveloped atom-economic and redox-neutral method to prepare enals. Applying a new electron poor self-assembling ligand system provides the first general rhodium-catalyst for the chemo- and stereoselective hydroformylation of dialkyl- as well as diaryl-substituted alkynes to furnish enals in excellent chemo- and stereoselectivity.
Porous organic polymer supported rhodium as a heterogeneous catalyst for hydroformylation of alkynes to α,β-unsaturated aldehydes
Liang, Zuyu,Chen, Jianbin,Chen, Xin,Zhang, Kai,Lv, Jinhe,Zhao, Haowen,Zhang, Guoying,Xie, Congxia,Zong, Lingbo,Jia, Xiaofei
supporting information, p. 13721 - 13724 (2019/11/19)
A new porous organic polymer supported rhodium catalyst (Rh/POL-BINAPa&PPh3) has been developed for the hydroformylation of various alkynes to afford the corresponding α,β-unsaturated aldehydes with high chem- and stereoselectivity, excellent catalytic activity and good reusability (10 cycles). The heterogeneous catalyst exhibited more catalytic activity than the comparable homogeneous Rh/BINAPa/PPh3 system.
Syngas-Free Highly Regioselective Rhodium-Catalyzed Transfer Hydroformylation of Alkynes to α,β-Unsaturated Aldehydes
Tan, Guangying,Wu, Yimin,Shi, Yang,You, Jingsong
supporting information, p. 7440 - 7444 (2019/05/15)
The hydroformylation of alkynes is a fundamental and important reaction in both academic research and industry. Conventional methods focus on the conversion of alkynes, CO, and H2 into α,β-unsaturated aldehydes, but they often suffer from problems associated with operation, regioselectivity, and chemoselectivity. Herein, we disclose an operationally simple, mild, and syngas-free rhodium-catalyzed reaction for the hydroformylation of alkynes via formyl and hydride transfer from an alkyl aldehyde. This synthetic method uses inexpensive and easy-to-handle n-butyraldehyde to overcome the challenge posed by the use of syngas in traditional approaches and employs a commercially available catalyst and ligand to transform a broad range of internal alkynes, especially alkynyl-containing complex molecules, into versatile stereodefined α,β-unsaturated aldehydes with excellent chemo-, regio-, and stereoselectivity.
Selective rhodium-catalyzed hydroformylation of alkynes to α,β-unsaturated aldehydes with a tetraphosphoramidite ligand
Zhang, Zongpeng,Wang, Qian,Chen, Caiyou,Han, Zhengyu,Dong, Xiu-Qin,Zhang, Xumu
supporting information, p. 3290 - 3293 (2016/07/13)
A tetraphosphoramidite ligand was successfully applied to a Rh-catalyzed hydroformylation of various symmetrical and unsymmetrical alkynes to afford corresponding α,β-unsaturated aldehyde products in good to excellent yields (up to 97% yield). Excellent chemo- and regioselectivities and high activities (up to 20 000 TON) were achieved. The corresponding α,β-unsaturated aldehyde products can be transformed into many useful and important organic molecules, such as indenamine derivatives and lukianol pyrroles. This great performance makes the hydroformylation of alkynes highly practical with great potential.
Selective palladium-catalyzed hydroformylation of alkynes to α,β-Unsaturated Aldehydes
Fang, Xianjie,Zhang, Min,Jackstell, Ralf,Beller, Matthias
, p. 4645 - 4649 (2013/05/22)
Atom-efficient: A selective palladium catalyst system is used for the hydroformylation of alkynes (see picture). In this syngas reaction, various alkynes were smoothly transformed to synthetically interesting α,β-unsaturated aldehydes in good yields with high regio- and stereoselectivity. Copyright
Rhodium-katalysierte Hydroformylierung innerer Alkine zu α,β-ungesaettigten Aldehyden
Johnson, John R.,Cuny, Gregory D.,Buchwald, Stephen L.
, p. 1877 - 1879 (2007/10/03)
Keywords: Alkine; Hydroformylierungen; Katalyse; Alkene; Rhodiumverbindungen
