888327-31-9

Upstream product

• 909793-64-2 (R,S)-4-chlorosulfonyl-indan-2-carboxylic acid 
• 934760-93-7 cis-3,5-dimethyl-1-(4-trifluoromethoxy-phenyl)-piperazine hydrochloride 
• 888327-29-5 (RS)-4-chlorosulfonyl-indan-2-carboxylic acid methyl ester 
• 866787-30-6 3,5-dimethyl-1-(4-trifluoromethoxy-phenyl)-piperazine 

Downstream Products

• 1016982-66-3 (S)-4-[cis-2,6-dimethyl-4-(4-trifluoromethoxy-phenyl)-piperazine-1-sulfonyl]-indan-2-carboxylic acid methyl ester 

Relevant academic research and scientific papers

SULFONYL-SUBSTITUTED BICYCLIC COMPOUNDS AS PPAR MODULATORS FOR THE TREATMENT OF NON-ALCOHOLIC STEATOHEPATITIS

Disclosed herein are new methods of treatment of non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and other fibrotic diseases of the liver in a subject by modulating PPARδ with sulfonyl-substituted bicyclic compounds and co

METHODS FOR THE MODULATION OF CRP BY THE SELECTIVE MODULATION OF PPAR DELTA

The present invention discloses methods to reduce C-reactive protein (CRP) in patients in need thereof comprising the selective modulation of PPARδ.

METHODS FOR THE UPREGULATION OF GLUT4 VIA MODULATION OF PPAR DELTA IN ADIPOSE TISSUE AND FOR THE TREATMENT OF DISEASE

The present invention is directed to novel compositions and their application as pharmaceuticals for the treatment of disease. Methods of upregulation of GLUT4 via activation of peroxisome proliferator activated receptor delta activity in the adipose tiss