888328-91-4

Upstream product

• 888328-90-3 4-bromo-1-isobutyl-7-methoxy-6-methyl-indan 
• 434300-54-6 4-(2-cyanoethyl)-2-isobutylphenyl trifluoromethanesulfonate 
• 71846-67-8 6-Methyl-7-methoxy-1-indanon 
• 888328-89-0 1-isobutyl-7-methoxy-6-methyl-indan 

Downstream Products

• 888328-92-5 C₂₈H₃₄F₃NO₃S 
• 888328-95-8 3-{4-[7-(3-benzyl-4-cyanomethoxy-phenyl)-1-isobutyl-6-methyl-indan-4-yl]-3-isobutyl-phenyl}-propionitrile 
• 888328-94-7 3-{4-[7-(3-benzyl-4-methoxy-phenyl)-1-isobutyl-6-methyl-indan-4-yl]-3-isobutyl-phenyl}-propionitrile 

Relevant academic research and scientific papers

α-Helix mimetics: Outwards and upwards

α-Helices are common secondary structural elements forming key parts of the large, generally featureless interfacial regions of many therapeutically-relevant protein-protein interactions (PPIs). The rational design of helix mimetics is an appealing small-

Diphenylindane-based proteomimetics reproduce the projection of the i, i+3, i+4, and i+7 residues on an α-helix

The design of a nonpeptidic scaffold based on 4,7-diphenyl-1,6- disubstituted indanes mimicking i, i+3, i+4, and i+7 residues of an α-helix has been described, and its synthesis has been accomplished. This strategy makes general approaches possible to hel