88855-24-7

Usage

Type of compound

Penta-3,4-dien-1-one derivative

Substituent

Pyrrolidin-1-yl

Potential applications

Medicinal chemistry and drug development

Function

Acts as a ligand for various biological targets (receptors and enzymes)

Potential use

Building block for the synthesis of other organic compounds

Current state of research

Exact properties and potential uses not fully characterized, requiring further study

Structure

Contains a pentadiene group and a pyrrolidine ring attached to a carbonyl group

Chemical properties

May exhibit reactivity due to the presence of the carbonyl group and the conjugated diene system

Biological activity

May interact with various biological targets, potentially leading to pharmaceutical applications

Upstream product

• 88855-23-6 1-acetylpyrrolidine diethyl acetal 
• 107-19-7 propargyl alcohol 
• 30332-99-1 penta-3,4-dienoic acid ethyl ester 
• 123-75-1 pyrrolidine 
• 60053-24-9 penta-3,4-dienoic acid 
• 4030-18-6 N-(acetyl)pyrrolidine 

Relevant academic research and scientific papers

Chemoselective γ-Oxidation of β,γ-Unsaturated Amides with TEMPO

A chemoselective and robust protocol for the γ-oxidation of β,γ-unsaturated amides is reported. In this method, electrophilic amide activation, in a rare application to unsaturated amides, enables a regioselective reaction with TEMPO resulting in the title products. Radical cyclisation reactions and oxidation of the synthesised products highlight the synthetic utility of the products obtained.

A Facile Synthesis of 3,4-Dienamides by the Reaction of Propargyl Alcohols with Cyclic Amide Acetals and Their Stereoselective Rearrangement to 2(E),4(Z)-Dienamides Promoted with Alumina. Total Synthesis of Isochavicine

Thermal condensation of propargyl alcohols with acetals of 1-acetylpyrrolidine and 1-acetylpiperidine gave 3,4-dienamides in good yields.Alumina promoted the rearrangement of β-allenic amides to 2(E),4(Z)-dienamides stereoselectively.Its application to the synthesis of isochavicine of pepper components is described.Carbon-13 NMR data of these dienamides were obtained.