888703-97-7

Upstream product

• 672-13-9 2-hydroxy-5-methoxybenzaldehyde 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 41951-76-2 2-hydroxy-5-methoxybenzyl alcohol 

Downstream Products

• 888703-98-8 2-(4'-aminophenyl)-5-methoxybenzo[b]furan 
• 1287783-17-8 4-(5-(2-(2-(2-⁽¹⁸⁾F-fluoroethoxy)ethoxy)ethoxy)benzofuran-2-yl)-N-methylbenzenamine 
• 1287783-15-6 4-(5-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)benzofuran-2-yl)-N-methylbenzenamine 
• 1287783-14-5 tert-butyl 4-(5-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)benzofuran-2-yl)phenyl-N-methylcarbamate 
• 1287783-13-4 tert-butyl 4-(5-(2-(2-(2-methanesulfonylethoxy)ethoxy)ethoxy)benzofuran-2-yl)phenyl-N-methylcarbamate 
• 1287783-12-3 tert-butyl 4-(5-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)benzofuran-2-yl)phenyl-N-methylcarbamate 
• 1287783-11-2 tert-butyl 4-(5-(2-(2-(2-(tert-butyldimethylsilyloxy)ethoxy)ethoxy)ethoxy)benzofuran-2-yl)phenyl-N-methylcarbamate 
• 1287783-10-1 4-(5-(2-(2-(2-(tert-butyldimethylsilyloxy)ethoxy)ethoxy)ethoxy)benzofuran-2-yl)-N-methylbenzenamine 
• 1287783-09-8 2-(2-(2-(2-(4-(methylamino)phenyl)benzofuran-5-yloxy)ethoxy)ethoxy)ethanol 
• 888704-00-5 [4-(5-methoxy-benzofuran-2-yl)-phenyl]-methyl-amine 
• 888703-99-9 2-(4-amino-phenyl)-benzofuran-5-ol 

Relevant academic research and scientific papers

Novel benzofuran derivatives for PET imaging of β-amyloid plaques in Alzheimer's disease brains

A novel series of benzofuran derivatives as potential positron emission tomography (PET) tracers targeting amyloid plaques in Alzheimer's disease (AD) were synthesized and evaluated. The syntheses of benzofurans were successfully achieved by an intramolec

Synthesis of Benzo[ b]furans by Intramolecular C-O Bond Formation Using Iron and Copper Catalysis

One-pot processes for the synthesis of benzo[b]furans from 1-aryl- or 1-alkylketones using nonprecious transition metal catalysts have been developed. Regioselective iron(III)-catalyzed halogenation of the aryl ring, followed by iron- or copper-catalyzed O-arylation allowed the synthesis of various structural analogues, including the benzo[b]furan-derived natural products corsifuran C, moracin F, and caleprunin B.

Novel 18F-labeled benzofuran derivatives with improved properties for positron emission tomography (PET) imaging of β-amyloid plaques in Alzheimer's brains

In vivo imaging of β-amyloid plaques in the brain may lead to the early diagnosis of Alzheimer's disease (AD) and monitoring of the progression and effectiveness of treatment. In the present study, we report on the development of two potential PET probes,

Novel benzofurans with 99mTc complexes as probes for imaging cerebral β-amyloid plaques

Two novel benzofuran derivatives coupled with 99mTc complexes were tested as probes for imaging cerebral β-amyloid plaques using single photon emission tomography. Although both derivatives bound to Aβ(1-42) aggregates, 99mTc-BAT-BF

ISOTOPICALLY-LABELED BENZOFURAN COMPOUNDS AS IMAGINGAGENTS FORAMYLOIDOGENIC PROTEINS

Benzofuran compounds which contain at least one detectable label selected from the group consisting of 131I, 123I, 124I, 125I, 76Br, 75Br, 18F, 19F, 11C, s