888705-45-1

Upstream product

• 888705-44-0 N¹-(2,6-diisopropylphenyl)ethane-1,2-diamine 
• 122-51-0 orthoformic acid triethyl ester 
• 50-00-0 formaldehyd 
• 131543-46-9 Glyoxal 
• 24544-04-5 2,6-diisopropylbenzenamine 
• 20781-86-6 N-(2,6-diisopropylphenyl)-2-chloroacetamide 
• 909030-52-0 2-azido-N-(2',6'-diisopropylphenyl)acetamide 
• 149-73-5 trimethyl orthoformate 

Downstream Products

• 1414649-04-9 (R)-3-(2,6-diisopropylphenyl)-1-((4-isopropyl-4,5-dihydrooxazol-2-yl)methyl)-4,5-dihydro-1H-imidazol-3-ium hexafluorophosphate 
• 1236112-44-9 3-bromopropyl-1-[3-(2,6-diisopropylphenyl)-4,5-dihydro-1H-imidazolium] bromide 
• 1236112-55-2 3-chloropropyl-1-[3-(2,6-diisopropylphenyl)-4,5-dihydro-1H-imidazolium] bromide 

Relevant academic research and scientific papers

Palladium(II) pyrazolyl–pyridyl complexes containing a sterically hindered N-heterocyclic carbene moiety for the Suzuki-Miyaura cross-coupling reaction

Cationic palladium complexes stabilized by a tridentate neutral {N,N,C} ligand containing a sterically hindered N-heterocyclic carbene (NHC) moiety have been prepared and characterized. The nature of the anionic counterion in the palladium complex has been varied to get crystals suitable for X-ray diffraction. The square planar structure of one of these complexes along with the axial contribution of the sterically hindered NHC fragment has been confirmed by X-ray analysis. In addition, all the isolated [{κ3-N,N,C}PdIICl]+X? [X? = Cl, PF6, BF4, B(C6H3Cl2)4] ion pairs have been scrutinized as catalysts in the cross-coupling Suzuki-Miyaura reaction between phenylboronic acid and variably substituted halo-aryl acceptors. Selected issues from this series have shown improved catalyst turn-over frequencies (TOFs) with respect to structurally related catalytic systems of the state-of-the-art.

Synthesis, Structural Characterization and Catalytic Activities of Sulfur-Functionalized NHC–Copper(I) Complexes

The synthesis of a family of N-heterocyclic carbene–copper complexes bearing a sulfur moiety by using different copper(I) halides through convenient procedures is reported. The solid-state structures of the presented copper compounds were elucidated based

A comparison between oxazoline-imidazolinylidene, -imidazolylidine, -benzimidazolylidene hydrogenation catalysts

Imidazolinylidene, imidazolylidine, benzimidazolylidene complexes 1a-c were prepared and tested in asymmetric hydrogenations of a series of largely unfunctionalized alkenes. Similarities and differences in the catalytic performance of these complexes were rationalized in terms of the predicted mechanisms of these reactions, and their relative tendencies to generate protons under the hydrogenation conditions.

Modular trimethylene-linked bisimidazol(in)ium salts

A short and modular synthesis of symmetrically and non-symmetrically substituted bisimidazolinylene N-heterocyclic carbene precursors is described. Two methods to establish dicopper(I) complexes of these compounds depending on the steric shielding of the

Steric variations between the synthesis of a stable chiral C 2-symmetric diimidazolidinylidene and an electron-rich tetraazafulvalene

C2-Symmetric electron-rich olefin dimers and imidazolidinylidene ligands with a 2,2-dimethyl-1,3-dioxolane backbone were synthesised and characterised. The steric protection of the carbene dictates which product is obtained. Georg Thieme Verlag

Modular synthesis of heterocyclic carbene precursors

A series of N-heterocyclic carbene precursors, containing an imidazoline or tetrahydropyrimidine framework, were prepared from ω-chloroalkanoyl chlorides. The sequential attachment of nitrogen nucleophiles and subsequent ring closure gave, depending on the reagents used, either the desired dihydroimidazolium and tetrahydropyrimidinium salts or their parent heterocycles. In this latter case, the second substituent was introduced in an alkylation step. The preparation of carbene precursors bearing chiral or bulky substituents was achieved with comparable efficiency.