888736-24-1

Basic information

• Product Name: [1-(3-iodo-benzoyl)-piperidin-4-yl]-acetic acid ethyl ester
• Synonyms: [1-(3-iodo-benzoyl)-piperidin-4-yl]-acetic acid ethyl ester
• CAS NO: 888736-24-1
• Molecular Weight: 401.244
• Mol File: 888736-24-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [1-(3-iodo-benzoyl)-piperidin-4-yl]-acetic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [1-(3-iodo-benzoyl)-piperidin-4-yl]-acetic acid ethyl ester(888736-24-1)
• EPA Substance Registry System: [1-(3-iodo-benzoyl)-piperidin-4-yl]-acetic acid ethyl ester(888736-24-1)

Safety Data

• Hazardous Substances Data: 888736-24-1(Hazardous Substances Data)

Upstream product

• 40110-55-2 ethyl 2-(1-benzylpiperidine-4-ylidene)acetate 
• 3612-20-2 1-phenylmethyl-4-piperidone 
• 59184-90-6 ethyl (piperidin-4-yl)acetate 
• 1711-10-0 3-iodobenzoyl chloride 

Downstream Products

• 888736-26-3 [1-(3-pyridin-2-ylethynyl-benzoyl)-piperidin-4-yl]-acetic acid 
• 888736-25-2 [1-(3-pyridin-2-ylethynyl-benzoyl)-piperidin-4-yl]-acetic acid ethyl ester 

Relevant articles and documents

Diarylacetylene piperidinyl amides as novel anxiolytics

N-Phenyl-2-[1-[3-(2-pyridinylethynyl)benzoyl]-4-piperidine]acetamide (9) and related piperidine acetamide derivatives have good oral activity in the elevated plus maze, an animal model predictive of clinical efficacy for the treatment of anxiety. Modest affinity was observed for the neurokinin NK-1 and 2 receptors, which are known to be involved in the regulation of mood and emotion.