888738-18-9 Usage
Uses
Used in Organic Synthesis:
(2-Bromo-6-trifluoromethyl-pyridin-3-yl)-methanol is used as a reagent in various organic synthesis reactions, contributing to the formation of complex organic molecules.
Used in Pharmaceutical Production:
(2-Bromo-6-trifluoromethyl-pyridin-3-yl)-methanol is used as an intermediate in the production of pharmaceuticals, playing a crucial role in the synthesis of certain drugs.
Used in Agrochemical Production:
(2-Bromo-6-trifluoromethyl-pyridin-3-yl)-methanol is also used as an intermediate in the production of agrochemicals, aiding in the development of agricultural products.
Used in Medicinal Chemistry and Drug Discovery:
Due to its unique structure and reactivity, (2-Bromo-6-trifluoromethyl-pyridin-3-yl)-methanol is used in medicinal chemistry and drug discovery for the development of new therapeutic agents.
It is important to handle (2-Bromo-6-trifluoromethyl-pyridin-3-yl)-methanol with proper care and to follow safe handling procedures due to its potential hazards and health risks, including irritation to the skin, eyes, and respiratory system.
Check Digit Verification of cas no
The CAS Registry Mumber 888738-18-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,8,7,3 and 8 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 888738-18:
(8*8)+(7*8)+(6*8)+(5*7)+(4*3)+(3*8)+(2*1)+(1*8)=249
249 % 10 = 9
So 888738-18-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H5BrF3NO/c8-6-4(3-13)1-2-5(12-6)7(9,10)11/h1-2,13H,3H2
888738-18-9Relevant academic research and scientific papers
A process for preparing 3 - substituted -2 - bromo -6 - trifluoromethyl pyridine
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Paragraph 0026; 0027; 0028, (2019/02/02)
The invention discloses a method of preparing 3-substituted-2-bromo-6-trifluoromethyl pyridine. The method comprises the following steps: in the presence of nitrogen, reacting 2-bromo-6-trifluoromethyl pyridine used as a raw material with lithium diisopropylamide at a low temperature to generate 3-site lithium salt, and then adding trimethyl borate, ethyl formate and carbon dioxide respectively to generate 2-bromo-6-trifluoromethyl-3-pyridineboronic acid, 2-bromo-6-trifluoromethyl-3-pyridylaldehyde and 2-bromo-6-trifluoromethyl-3-picolinic acid; and reducing 2-bromo-6-trifluoromethyl-3-pyridylaldehyde by sodium borohydride to generate 2-bromo-6-trifluoromethyl-3-pyridinemethanol. The generated target compound is high in yield and good in purity, is an important medical intermediate, and has a wide application prospect. The method disclosed by the invention is simple and convenient to operate, easily available in raw materials, good in reaction selectivity, environment-friendly, easy for enlarged production, and capable of realizing commercialized products.
DIBENZYL AMINE COMPOUNDS AND DERIVATIVES
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Page/Page column 58; 59, (2008/06/13)
Dibenzyl amine compounds and derivatives, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid le
