1192263-89-0

Basic information

• Product Name: 2-broMo-6-(trifluoroMethyl)pyridine-3-carbaldehyde
• Synonyms: 2-broMo-6-(trifluoroMethyl)pyridine-3-carbaldehyde;2-Bromo-6-(trifluoromethyl)nicotinaldehyde 85+%;2-Bromo-6-(trifluoromethyl)pyridine-3-carboxaldehyde, 2-Bromo-3-formyl-6-(trifluoromethyl)pyridine
• CAS NO: 1192263-89-0
• Molecular Formula: C7H3BrF3NO
• Molecular Weight: 254.0040296
• Mol File: 1192263-89-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 245.8±40.0 °C(Predicted)
• Appearance: /
• Density: 1.763±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: -5.70±0.22(Predicted)
• CAS DataBase Reference: 2-broMo-6-(trifluoroMethyl)pyridine-3-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-broMo-6-(trifluoroMethyl)pyridine-3-carbaldehyde(1192263-89-0)
• EPA Substance Registry System: 2-broMo-6-(trifluoroMethyl)pyridine-3-carbaldehyde(1192263-89-0)

Safety Data

• Hazardous Substances Data: 1192263-89-0(Hazardous Substances Data)

Usage

General Description

2-bromine-6-trifluoromethylpyridine-3-carbaldehyde is a chemical compound with the molecular formula C8H4BrF3NO. It is a pyridine derivative with a bromine atom attached to the 2 position, a trifluoromethyl group attached to the 6 position, and a carbaldehyde group attached to the 3 position. 2-broMo-6-(trifluoroMethyl)pyridine-3-carbaldehyde is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also used in research and development of new chemical compounds for various applications. 2-bromine-6-trifluoromethylpyridine-3-carbaldehyde is a versatile building block in organic chemistry and has potential for use in a wide range of industrial and scientific processes.

Upstream product

• 189278-27-1 2-bromo-6-(trifluoromethyl)pyridine 
• 109-94-4 formic acid ethyl ester 

Downstream Products

• 888738-18-9 (2-bromo-6-(trifluoromethyl)pyridin-3-yl)methanol 

Relevant articles and documents

A process for preparing 3 - substituted -2 - bromo -6 - trifluoromethyl pyridine

The invention discloses a method of preparing 3-substituted-2-bromo-6-trifluoromethyl pyridine. The method comprises the following steps: in the presence of nitrogen, reacting 2-bromo-6-trifluoromethyl pyridine used as a raw material with lithium diisopropylamide at a low temperature to generate 3-site lithium salt, and then adding trimethyl borate, ethyl formate and carbon dioxide respectively to generate 2-bromo-6-trifluoromethyl-3-pyridineboronic acid, 2-bromo-6-trifluoromethyl-3-pyridylaldehyde and 2-bromo-6-trifluoromethyl-3-picolinic acid; and reducing 2-bromo-6-trifluoromethyl-3-pyridylaldehyde by sodium borohydride to generate 2-bromo-6-trifluoromethyl-3-pyridinemethanol. The generated target compound is high in yield and good in purity, is an important medical intermediate, and has a wide application prospect. The method disclosed by the invention is simple and convenient to operate, easily available in raw materials, good in reaction selectivity, environment-friendly, easy for enlarged production, and capable of realizing commercialized products.