88881-74-7 Usage
Description
Ethyl 2-(4-acetamidophenyl)sulfonylacetate is a chemical compound that belongs to the class of sulfonamide derivatives, known for their wide range of biological and pharmaceutical activities. This particular compound is a sulfonylacetate derivative with a phenyl and acetamido substituent at the 2 and 4 positions, respectively. It is recognized for its potential as an anti-inflammatory, analgesic, and antipyretic agent, and has been studied for its potential use in treating various medical conditions such as pain, inflammation, and fever. Ethyl 2-(4-acetamidophenyl)sulfonylacetate is a versatile compound with significant applications in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
Ethyl 2-(4-acetamidophenyl)sulfonylacetate is used as a pharmaceutical intermediate for the synthesis of various drugs due to its unique chemical structure and biological activity.
Used in Anti-inflammatory Applications:
Ethyl 2-(4-acetamidophenyl)sulfonylacetate is used as an anti-inflammatory agent for its potential to reduce inflammation, which can be beneficial in treating conditions characterized by excessive inflammation.
Used in Analgesic Applications:
Ethyl 2-(4-acetamidophenyl)sulfonylacetate is used as an analgesic agent to alleviate pain, making it a candidate for the development of pain management medications.
Used in Antipyretic Applications:
Ethyl 2-(4-acetamidophenyl)sulfonylacetate is used as an antipyretic agent to reduce fever, which can be particularly useful in managing conditions associated with elevated body temperature.
Used in Treatment of Medical Conditions:
Ethyl 2-(4-acetamidophenyl)sulfonylacetate is used in the development of treatments for various medical conditions, including pain, inflammation, and fever, due to its demonstrated potential in these areas.
Check Digit Verification of cas no
The CAS Registry Mumber 88881-74-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,8,8 and 1 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 88881-74:
(7*8)+(6*8)+(5*8)+(4*8)+(3*1)+(2*7)+(1*4)=197
197 % 10 = 7
So 88881-74-7 is a valid CAS Registry Number.
InChI:InChI=1/C12H15NO5S/c1-3-18-12(15)8-19(16,17)11-6-4-10(5-7-11)13-9(2)14/h4-7H,3,8H2,1-2H3,(H,13,14)
88881-74-7Relevant articles and documents
Unique para-aminobenzenesulfonyl oxadiazoles as novel structural potential membrane active antibacterial agents towards drug-resistant methicillin resistant Staphylococcus aureus
Wang, Juan,Ansari, Mohammad Fawad,Zhou, Cheng-He
, (2021/04/12)
A class of structurally unique para-aminobenzenesulfonyl oxadiazoles as new potential antimicrobial agents was designed and synthesized from acetanilide. Some target para-aminobenzenesulfonyl oxadiazoles showed antibacterial potency. Noticeably, hexyl derivative 8b (MIC = 1 μg/mL) was more active than norfloxacin against drug resistant MRSA. Compound 8b was able to disturb the membrane effectively and intercalate into deoxyribonucleic acid (DNA) to form a steady 8b-DNA complex, which might be responsible for bacterial metabolic inactivation. Molecular docking indicated that 8b could interact with DNA topoisomerase IV through noncovalent interactions to form a supramolecular complex and hinder the function of this enzyme. These results indicated that hexyl derivative 8b deserved further investigation as a new lead compound.
