88901-36-4

Basic information

• Product Name: Mogroside V
• Synonyms: Momordica grosvenori swingle;(24R)-3β-[6-O-(β-D-Glucopyranosyl)-β-D-glucopyranosyloxy]-24-[2-O,6-O-bis(β-D-glucopyranosyl)-β-D-glucopyranosyloxy]cucurbit-5-ene-11α,25-diol;beta-D-Glucopyranoside, (3beta,9beta,10alpha,11alpha,24R)-3-((6-o-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy)-11,25-dihydroxy-9-methyl-19-norlanost-5-en-24-yl o-beta-D-glucopyranosyl-(1-2)-o-(beta-D-glucopyranosyl-(1-6))-;Mogrol-3-o-(beta-D-glucopyranosyl (1-6)-beta-D-glucopyranoside)-24-o-((beta-D-glucopyranosyl (1-2))-(beta-D-glucopyranosyl(1-6))-beta-D-glucopyranoside);MomordicagrosvenoriSwingleP.E;MOGROSIDE V(P);Mogroside V ,98%;Momordica grosvenori
• CAS NO: 88901-36-4
• Molecular Formula: C₆₀H₁₀₂O₂₉
• Molecular Weight: 1287.44
• EINECS: 695-005-3
• Product Categories: Food Additives;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Miscellaneous Natural Products;Inhibitors
• Mol File: 88901-36-4.mol
• Article Data: 1

Chemical Properties

• Melting Point: 197～201℃
• Appearance: yellow powder
• Density: 1.51
• Refractive Index: 1.643
• Storage Temp.: 2-8°C
• Solubility: Methanol (Slightly, Sonicated), Pyrindine (Slightly), Water (Slightly)
• PKA: 12.82±0.70(Predicted)
• Stability: Hygroscopic
• CAS DataBase Reference: Mogroside V(CAS DataBase Reference)
• NIST Chemistry Reference: Mogroside V(88901-36-4)
• EPA Substance Registry System: Mogroside V(88901-36-4)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 88901-36-4(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Uses

Mogroside V is used as a natural sweetener. Existing as a triterpenoidal saponina from the fruit of Siraitia grosvenorii Swingle, mogrosides are often used as a substitute for sugar by the food industry. Also acts as a potential anti-inflammatory for the lung airway.

InChI:InChI=1/C60H102O29/c1-23(9-13-35(57(4,5)79)88-55-50(89-54-49(78)43(72)38(67)29(20-63)84-54)45(74)40(69)31(86-55)22-81-52-47(76)42(71)37(66)28(19-62)83-52)24-15-16-58(6)32-12-10-25-26(60(32,8)33(64)17-59(24,58)7)11-14-34(56(25,2)3)87-53-48(77)44(73)39(68)30(85-53)21-80-51-46(75)41(70)36(65)27(18-61)82-51/h10,23-24,26-55,61-79H,9,11-22H2,1-8H3/t23-,24-,26-,27-,28-,29+,30?,31-,32+,33-,34+,35?,36-,37-,38+,39-,40-,41+,42+,43-,44+,45+,46-,47-,48-,49+,50-,51-,52-,53+,54-,55+,58+,59-,60+/m1/s1

Synthetic route

11-oxo-mogroside V → 11-epi-mogroside V + 3-O-β-D-glucopyranosyl-(1->6)-β-D-glucopyranosyl (24R)-cucurbit-5-ene-3β,11α,24,25-tetrol 24-O-β-D-glucopyranosyl-(1->2)-[β-D-glucopyranoside-(1->6)]-β-D-glucopyranoside (88901-36-4)

Conditions	Yield
With sodium tetrahydroborate In 1,4-dioxane at 50℃; for 72h;

3-O-β-D-glucopyranosyl-(1->6)-β-D-glucopyranosyl (24R)-cucurbit-5-ene-3β,11α,24,25-tetrol 24-O-β-D-glucopyranosyl-(1->2)-[β-D-glucopyranoside-(1->6)]-β-D-glucopyranoside (88901-36-4) → 3-O-β-D-glucopyranosyl-(1->6)-β-D-glucopyranosyl (24R)-cucurbit-5-en-11-one-3β,24,25-triol 24-O-β-D-glucopyranosyl-(1->2)-[β-D-glucopyranoside-(1->6)]-β-D-glucopyranoside

Conditions	Yield
With potassium permanganate In water for 1.5h; Reagent/catalyst;	96.71%

3-O-β-D-glucopyranosyl-(1->6)-β-D-glucopyranosyl (24R)-cucurbit-5-ene-3β,11α,24,25-tetrol 24-O-β-D-glucopyranosyl-(1->2)-[β-D-glucopyranoside-(1->6)]-β-D-glucopyranoside (88901-36-4) → D-glucose (50-99-7)

Conditions	Yield
With hydrogenchloride; water for 1.5h;

Downstream Products

• 50-99-7 D-glucose 

Relevant articles and documents

COMPOSITIONS

A sweetness modifying composition comprising at least one high-intensity sweetener chosen from steviol glycosides and/or mogrosides and at least one low-potency sweetener chosen from cellobiose, psicose, cyclamate and/or 11-O-mogroside V, and a sweetened composition comprising said sweetness modifying composition and at least one other sweetener; the uses of said sweetened compositions and sweetness modifying compositions; methods of making said sweetened compositions and sweetness modifying compositions.