88909-96-0

Basic information

• Product Name: 4-(N-(1,8-NAPHTHALIMIDO))-N-BUTYRIC ACID
• Synonyms: AKOS BBS-00007385;4-(N-(1,8-NAPHTHALIMIDO))-N-BUTYRIC ACID;4-(1,3-DIOXO-1H,3H-BENZO[DE]ISOQUINOLIN-2-YL)-BUTYRIC ACID;4-(1,3-DIOXO-1H-BENZO[DE]ISOQUINOLIN-2(3H)-YL)BUTANOIC ACID;VIRSTATIN;4-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-butyri acid;1H-Benz(de)isoquinoline-2(3H)-butanoic acid, 1,3-dioxo-;isodibut
• CAS NO: 88909-96-0
• Molecular Formula: C16H13NO4
• Molecular Weight: 283.28
• Mol File: 88909-96-0.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 536.5°C at 760 mmHg
• Flash Point: 278.3°C
• Appearance: /
• Density: 1.403g/cm³
• Vapor Pressure: 2.42E-12mmHg at 25°C
• Refractive Index: 1.672
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-(N-(1,8-NAPHTHALIMIDO))-N-BUTYRIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(N-(1,8-NAPHTHALIMIDO))-N-BUTYRIC ACID(88909-96-0)
• EPA Substance Registry System: 4-(N-(1,8-NAPHTHALIMIDO))-N-BUTYRIC ACID(88909-96-0)

Safety Data

• Hazardous Substances Data: 88909-96-0(Hazardous Substances Data)

Usage

Uses

inhibits virulence regulation in Vibrio cholerae, antiviral

InChI:InChI=1/C16H13NO4/c18-13(19)8-3-9-17-15(20)11-6-1-4-10-5-2-7-12(14(10)11)16(17)21/h1-2,4-7H,3,8-9H2,(H,18,19)

Upstream product

• 150705-10-5 ethyl 4-(1,3-dioxo-2,3-dihydro-1H-benzo[d,e]isoquinolin-2-yl)butanoate 
• 81-83-4 1,8-Naphthalimide 
• 81-84-5 1,8-Naphthalic anhydride 
• 56-12-2 4-amino-n-butyric acid 

Relevant articles and documents

Synthesis and photophysical properties of multichromophoric carbonyl-bridged triarylamines

The synthesis and photophysical properties of two novel multichromophoric compounds is presented. Their molecular design comprises a carbonyl-bridged triarylamine core and either naphthalimides or 4-(5-hexyl-2,2 -bithiophene)naphthalimides as second chrom

Target Enzyme-Activated Two-Photon Fluorescent Probes: A Case Study of CYP3A4 Using a Two-Dimensional Design Strategy

The rapid development of fluorescent probes for monitoring target enzymes is still a great challenge owing to the lack of efficient ways to optimize a specific fluorophore. Herein, a practical two-dimensional strategy was designed for the development of an isoform-specific probe for CYP3A4, a key cytochrome P450 isoform responsible for the oxidation of most clinical drugs. In first dimension of the design strategy, a potential two-photon fluorescent substrate (NN) for CYP3A4 was effectively selected using ensemble-based virtual screening. In the second dimension, various substituent groups were introduced into NN to optimize the isoform-selectivity and reactivity. Finally, with ideal selectivity and sensitivity, NEN was successfully applied to the real-time detection of CYP3A4 in living cells and zebrafish. These findings suggested that our strategy is practical for developing an isoform-specific probe for a target enzyme.

Structures of bifunctional molecules containing two very different supramolecular synthons: Carboxylic acid and strong π...π stacking 1,8-naphthalimide ring

A series of molecules containing a carboxylic acid and a 1,8-naphthalimide group joined by different linkers (HLC1 = CH2; HL C2 = CH2CH2; HLC3 = CH 2CH2CH2;