889101-41-1

Usage

Uses

Used in Pharmaceutical Industry:
(2R,3R,4aR)-2,3,4,4a-Tetrahydro-2,3,7-trihydroxy-9-Methoxy-4a-Methyl-6H-dibenzo[b,d]pyran-6-one is used as a pharmaceutical agent for its potential therapeutic effects. (2R,3R,4aR)-2,3,4,4a-Tetrahydro-2,3,7-trihydroxy-9-Methoxy-4a-Methyl-6H-dibenzo[b,d]pyran-6-one's unique structure and functional groups may allow it to interact with specific biological targets, such as enzymes or receptors, modulating their activity and contributing to the treatment of various diseases.
Used in Chemical Research:
In the field of chemical research, (2R,3R,4aR)-2,3,4,4a-Tetrahydro-2,3,7-trihydroxy-9-Methoxy-4a-Methyl-6H-dibenzo[b,d]pyran-6-one serves as a valuable compound for studying the synthesis, properties, and potential applications of dibenzo[b,d]pyran derivatives. Its complex structure and stereochemistry make it an interesting subject for exploring new synthetic routes and understanding the relationship between molecular structure and biological activity.
Used in Toxicological Studies:
(2R,3R,4aR)-2,3,4,4a-Tetrahydro-2,3,7-trihydroxy-9-Methoxy-4a-Methyl-6H-dibenzo[b,d]pyran-6-one may also be used in toxicological studies to investigate its potential toxicity and safety profile. Understanding the compound's effects on biological systems can help in assessing its suitability for various applications and guide the development of safer and more effective drugs or chemicals.

Upstream product

• 286936-09-2 (2'S,3'S,4R,5R)-4-O,5-O-(2',3'-dimethoxybutane-2',3'-diyl)-4,5-dihydroxycyclohex-2-en-1-one 
• 532394-17-5 7-methoxy-2,2-dimethyl-5-(trifluoromethylsulfonyloxy)benzo[1,3]dioxin-4-one 
• 888723-90-8 7-methoxy-2,2-dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4H-benzo[d][1,3]dioxin-4-one 
• 888723-95-3 (6aS,7aR,9S,10S,11aR)-4-hydroxy-2,9,10-trimethoxy-7a,9,10-trimethyl-6a,7,7a,9,10,11a-hexahydro-5H-benzo[c][1,4]dioxin[2,3-g]chromen-5-one 

Relevant academic research and scientific papers

First synthesis of (?)-altenuene-D3 suitable as internal standard for isotope dilution mass spectrometry

Metabolites from Alternaria fungi exhibit a variety of biological properties such as phytotoxic, cytotoxic, or antimicrobial activity. Optimization of a literature procedure culminated in an efficient total synthesis of (?)-altenuene as well as a stable isotope-labeled derivative suitable for implementation in a LC-MS/MS method for mycotoxin analysis.

Total synthesis of altenuene and isoaltenuene

Total synthesis of altenuene and isoaltenuene, toxins produced by various alternaria fungi, were achieved for the first time in ten steps, starting with quinic acid and commercially available acetal-protected phloroglucinic acid, with the longest linear sequence consisting of seven steps. The key reactions are palladium-catalyzed Suzuki-type couplings between an arene boronate and iodinated cyclohexenes. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.