(-)-Altenuene

Base Information

Chemical Name:(-)-Altenuene
CAS No.:889101-41-1
Molecular Formula:C₁₅H₁₆O₆
Molecular Weight:292.288
Hs Code.:29322090
European Community (EC) Number:814-111-4
Nikkaji Number:J513.108A
Wikidata:Q106042120
Mol file:889101-41-1.mol

Synonyms:(-)-Altenuene;889101-41-1;(2R,3R,4aR)-2,3,7-trihydroxy-9-methoxy-4a-methyl-3,4-dihydro-2H-benzo[c]chromen-6-one;(2R,3R,4aR)-2,3,4,4a-Tetrahydro-2,3,7-trihydroxy-9-methoxy-4a-methyl-6H-dibenzo[b,d]pyran-6-one;(2R,3R,4aR)-2,3,7-trihydroxy-9-methoxy-4a-methyl-2H,3H,4H,4aH,6H-benzo[c]chromen-6-one;HY-N6713A;CHEBI:144317;AKOS040740693;BA162707;CS-0144271;(+/-)-Altenuene 10 microg/mL in Acetonitrile;(2R,3R,4aR)-2,3,7-trihydroxy-9-methoxy-4a-methyl-2,3,4,4a-tetrahydro-6H-benzo[c]chromen-6-one;(2R,3R,4aR)-2,3,7-trihydroxy-9-methoxy-4a-methyl-2,3,4,4a-tetrahydro-6H-dibenzo[b,d]pyran-6-one;6H-Dibenzo[b,d]pyran-6-one, 2,3,4,4a-tetrahydro-2,3,7-trihydroxy-9-methoxy-4a-methyl-, (2?,3?,4a?)-;6H-Dibenzo[b,d]pyran-6-one, 2,3,4,4a-tetrahydro-2,3,7-trihydroxy-9-methoxy-4a-methyl-, (2?,3?,4a?)-(+/-)- (8CI);rel-(2R,3R,4aR)-2,3,4,4a-Tetrahydro-2,3,7-trihydroxy-9-methoxy-4a-methyl-6H-dibenzo[b,d]pyran-6-one;Altenuene;(+/-)-Altenuene

Suppliers and Price of (-)-Altenuene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(-)-Altenuene
1mg
$ 755.00

Medical Isotopes, Inc.
(-)-Altenuene
0.25 mg
$ 590.00

ChemScene
(-)-Altenuene
1mg
$ 820.00

Cayman Chemical
(-)-Altenuene ≥98%
1mg
$ 730.00

American Custom Chemicals Corporation
ALTENUENE 95.00%
5MG
$ 452.46

AK Scientific
(-)-Altenuene
1mg
$ 1011.00

Total 15 raw suppliers

Chemical Property of (-)-Altenuene

Chemical Property:

Melting Point:158 - 161°C
Boiling Point:609.4±55.0 °C(Predicted)
PKA:7.41±0.70(Predicted)
Density:1.49±0.1 g/cm3(Predicted)
Storage Temp.:Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Solubility.:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
XLogP3:0.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:292.09468823
Heavy Atom Count:21
Complexity:475

Purity/Quality:

99% ^*data from raw suppliers

(-)-Altenuene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC12CC(C(C=C1C3=C(C(=CC(=C3)OC)O)C(=O)O2)O)O
Isomeric SMILES:C[C@@]12C[C@H]([C@@H](C=C1C3=C(C(=CC(=C3)OC)O)C(=O)O2)O)O
Uses (-)-Altenuene is a toxin isolated from the fungus Alternaria tenuis. (-)-Altenuene is structurally related to Alternariol (A575760).

Technology Process of (-)-Altenuene

There total 10 articles about (-)-Altenuene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 888723-95-3
(6aS,7aR,9S,10S,11aR)-4-hydroxy-2,9,10-trimethoxy-7a,9,10-trimethyl-6a,7,7a,9,10,11a-hexahydro-5H-benzo[c][1,4]dioxin[2,3-g]chromen-5-one

: 887751-92-0,889101-41-1
(2R,3R,4aS)-2,3,7-trihydroxy-9-methoxy-4a-methyl-2,3,4,4a-tetrahydrobenzo[c]chromen-6-one

Guidance literature:: In water; trifluoroacetic acid; at 20 ℃; for 0.166667h;
DOI:10.1002/ejoc.200500904

Reference yield: 55.0%

: (6aR,7aR,9S,10S,11aR)-4-hydroxy-2,9,10-trimethoxy-7a,9,10-trimethyl-6a,7,7a,9,10,11a-hexahydro-5H-benzo[c][1,4]dioxin[2,3-g]chromen-5-one

: 889101-41-1
altenuene

Guidance literature:: In water; trifluoroacetic acid; at 20 ℃; for 0.166667h;
DOI:10.1002/ejoc.200500904

Reference yield:

: 286936-09-2
(2'S,3'S,4R,5R)-4-O,5-O-(2',3'-dimethoxybutane-2',3'-diyl)-4,5-dihydroxycyclohex-2-en-1-one

: 889101-41-1
altenuene

Guidance literature:: Multi-step reaction with 5 steps

1.1: bromine / dichloromethane / 1.5 h / 0 °C / Inert atmosphere

1.2: 1 h / 20 °C / Inert atmosphere

2.1: tetrahydrofuran; diethyl ether / 1 h / -78 - 20 °C / Inert atmosphere

3.1: triethylamine; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / tetrahydrofuran; water / 70 °C / Inert atmosphere

4.1: potassium carbonate / methanol / Inert atmosphere

5.1: acetic acid / water / Inert atmosphere

With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; bromine; potassium carbonate; acetic acid; triethylamine; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; water;
DOI:10.3390/molecules24244563