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CAS

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889110-20-7

4-(Bis-phenylsulfanyl-methylene)-5,5,6,6,6-pentafluoro-hexan-2-one is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 889110-20-7 Structure

  • Basic information

    1. Product Name: 4-(Bis-phenylsulfanyl-methylene)-5,5,6,6,6-pentafluoro-hexan-2-one
    2. Synonyms: 4-(Bis-phenylsulfanyl-methylene)-5,5,6,6,6-pentafluoro-hexan-2-one
    3. CAS NO:889110-20-7
    4. Molecular Formula:
    5. Molecular Weight: 418.452
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 889110-20-7.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-(Bis-phenylsulfanyl-methylene)-5,5,6,6,6-pentafluoro-hexan-2-one(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-(Bis-phenylsulfanyl-methylene)-5,5,6,6,6-pentafluoro-hexan-2-one(889110-20-7)
    11. EPA Substance Registry System: 4-(Bis-phenylsulfanyl-methylene)-5,5,6,6,6-pentafluoro-hexan-2-one(889110-20-7)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 889110-20-7(Hazardous Substances Data)

889110-20-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 889110-20-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,9,1,1 and 0 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 889110-20:
(8*8)+(7*8)+(6*9)+(5*1)+(4*1)+(3*0)+(2*2)+(1*0)=187
187 % 10 = 7
So 889110-20-7 is a valid CAS Registry Number.

889110-20-7Relevant articles and documents

Incorporation of a 3-(2,2,2-Trifluoroethyl)-γ-hydroxy-γ-lactam motif in the side chain of 4-aminoquinolines. Syntheses and antimalarial activities

Cornut, Damien,Lemoine, Hugues,Kanishchev, Oleksandr,Okada, Etsuji,Albrieux, Florian,Beavogui, Abdoul Habib,Bienvenu, Anne-Lise,Picot, Stéphane,Bouillon, Jean-Philippe,Médebielle, Maurice

, p. 73 - 83 (2013/02/23)

In this paper we report the synthesis and antimalarial properties of two series of fluoroalkylated γ-lactams derived from 4-aminoquinoline as potent chemotherapeutic agents for malaria treatment. These molecules obtained in several steps resulted in the identification of very potent structures with in vitro activity against Plasmodium falciparum clones of variable sensitivity (3D7 and W2) in the range of 19-50 nM with resistance indices in the range of 1.0-2.5. In addition, selected molecules (50, 51, 58, 60, 63, 70, 72, 74, 78, 81, 84, and 87) that are representative of the two series of compounds did not show cytotoxicity in vitro when tested against human umbilical vein endothelial cells up to a concentration of 100 μM. The most promising compounds (82 and 84) showed significant IC50 values close to 26 and 19 nM against the chloroquino-sensitive strain 3D7 and 49 and 42 nM against the multi-drug-resistant strain W2. Furthermore, two model compounds (50 and 70) were found to be quite stable over 48 h at pH 7.4 and 5.2. Overall, our preliminary data indicate that this class of structures contains promising candidates for further study.

Synthesis of new trifluoromethylated furans, dihydrofurans and butenolides starting from γ-ketothioesters and diisopropylamine

Bouillon, Jean-Philippe,Kikelj, Vincent,Tinant, Bernard,Harakat, Dominique,Portella, Charles

, p. 1050 - 1056 (2007/10/03)

γ-Ketothioesters were easily transformed into furans, dihydrofurans or butenolides by simple treatment with diisopropylamine in diethyl ether. The substitution pattern of the starting material has a great influence on the outcome of the reaction. Possible

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