88912-74-7Relevant academic research and scientific papers
1-(2-Aminoethyl)-3-(arylsulfonyl)-1H-pyrrolopyridines are 5-HT6 receptor ligands
Bernotas, Ronald C.,Antane, Schuyler A.,Lenicek, Steven E.,Haydar, Simon N.,Robichaud, Albert J.,Harrison, Boyd L.,Zhang, Guo Ming,Smith, Deborah,Coupet, Joseph,Schechter, Lee E.
scheme or table, p. 6935 - 6938 (2010/06/16)
1-(2-Aminoethyl)-3-(arylsulfonyl)-1H-pyrrolopyridines were prepared. Binding assays indicated they are 5-HT6 receptor ligands, among which 6f and 6g showed high affinity for 5-HT6 receptors with Ki = 3.9 and 1.7 nM, respectively.
Heterocyclyl-3-sulfonylazaindole or-azaindazole derivatives as 5-hydroxytryptamine-6 ligands
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Page 10, (2008/06/13)
The present invention provides a compound of formula I and the use thereof for the treatment of a central nervous system disorder related to or affected by the 5-HT6 receptor.
Vicarious Nucleophilic Substitution of Hydrogen in Nitropyridines by α-Chloroalkyl Phenyl Sulfone Carbanions
Makosza, Mieczyslaw,Chylinska, Barbara,Mudryk, Bogustaw
, p. 8 - 14 (2007/10/02)
Nitropyridines and chloronitropyridines react with carbanions of α-chloroalkyl phenyl sulfones yielding products of the vicarious nucleophilic substitution of hydrogen at positions ortho and para to the nitro group.A general rule that the vicarious substi
