88912-85-0

Upstream product

• 39103-38-3 (E)-2-styrylchromone 
• 109-77-3 malononitrile 
• 51138-54-6 2-styryl-4-thiochromone 
• 15058-15-8 2-(2-methyl-4H-1-benzopyran-4-ylidene)propanedinitrile 
• 100-52-7 benzaldehyde 
• 88912-83-8 9-<2-(2-Phenylethenyl)-4H-1-benzopyran-4-ylidene>-9H-xanthene 
• 88912-81-6 4-Diphenylmethylene-2-(2-phenylethenyl)-4H-1-benzopyran 

Relevant academic research and scientific papers

Dicyanomethylene AIE pyran molecule with - 4H - effect Construction method and application

The invention provides DM-based fluorophore F1 - F5 and Cu having AIE effects. 2 + The fluorescent probe FP1, based on dicyanomethylene - 4H - pyran (DM), generally appears as a fluorescent quenching effect, and discloses a preparation method and application of five fluorophores (F1 - F5) with aggregation-induced emission (AIE) properties and a copper ion fluorescent probe (FP1) based on F1. To the invention, the fluorescent probe FP1 is generated by coupling the terpyridine with F1 as an identification group. In 90% -THF with water content H2 In the mixed solution O, the probe FP1 exhibits a stronger fluorescence emission and contains Cu. 2 + When an aqueous solution of pyridine is complexed with it, fluorescence quenching is caused. The probe is Cu in an aqueous solution. 2 + The detection method has a certain application value.

Reactions with 2-Methyl- and 2-Styryl-4-thiochromones

Diazoalkanes react with 2-methyl- and 2-styryl-4-thiochromones to yield the 1,3-dithiolanes 1 and/or ethylenes 2-4.The latter are cleaved with thionyl chloride to give the corresponding ketones, while on fusion with sulfur they afford the corresponding thioketones.By condensation with compounds containing active hydrogen, such as malononitrile and ethyl cyanoacetate, the 2-methyl- and 2-styryl-4-thiochromones yield the compounds 5.Oxidation of 2-methyl- and 2-styryl-4-thiochromones was accomplished by yellow mercury(II) oxide as well as with tetrahalo-o-benzoquinones to give the corresponding ketones.The biological activity of some selected comounds prepared during this work has been tested towards Gram-positive and Gram-negative bacteria.