88913-69-3Relevant academic research and scientific papers
Potential Antitumor Agents. 47. 3'-Methylamino Analogues of Amsacrine with in Vivo Solid Tumor Activity
Atwell, Graham, J.,Baguley, Bruce C.,Finlay, Graeme J.,Rewcastle, Gordon W.,Denny, William A.
, p. 1769 - 1776 (2007/10/02)
Replacement of the 3'-methoxy group of the clinical antileukemic agent amsacrine (1) with a 3'-methylamino group provides a compound (3) with a broader spectrum of action, including in vivo activity against experimental solid tumors.The synthesis, physico
