889134-10-5Relevant academic research and scientific papers
Photochemical transformations of chalcone-podands into cyclobutane- containing benzocrown ethers
Ovchinnikova,Fedorova,Matochkina,Kodess,Slepukhin,Rusinov
scheme or table, p. 1180 - 1191 (2010/10/04)
A method for the synthesis of cyclobutane-containing benzocrown ethers by the template photocycloaddition of the corresponding chalcone-podands in solutions was developed. It was shown by X-ray diffraction analysis, 1H and 13C NMR, and UV spectroscopy tha
Novel bis(1-acyl-2-pyrazolines) of potential anti-inflammatory and molluscicidal properties
Barsoum, Flora F.,Hosni, Hanaa M.,Girgis, Adel S.
, p. 3929 - 3937 (2007/10/03)
A variety of bis[3-aryl-4,5-dihydro-1H-pyrazol-1-carboxaldehydes] 4a-h were obtained via reaction of bis[1-aryl-2-propen-1-ones] 3a-h with hydrazine hydrate in refluxing formic acid. In addition, the corresponding bis[1-acetyl-3-aryl-4,5-dihydro-1H-pyrazo
Difunctional Heterocycles: A Convenient Synthesis of Bis(4,5-dihydropyrazolyl) ethers from Their Precursors Bis(chalcones)
Elwahy, Ahmed H. M.
, p. 2582 - 2596 (2007/10/03)
The new bis(4,5-dihydropyrazolyl)ethers 18-22, 26, 27 and 40-44 were prepared in 30-80 percent yields by condensation of the corresponding bis(chalcones) 13-17 and 34-37 with each of hydrazine and phenylhydrazine. Attemptes to prepare compound 20 by alkylation of 24 with 1,4-dibromobutane were unsuccessful and instead the monoalkylated derivatives 25 was obtained in 45 percent yield. Compound 24 was obtained in 63 percent yield by reacting 23 with hydrazine hydrate in refluxing acetic acid. The bis(chalcones) 13-17 and 34-37 were obtained in 65-80 percent yields by basic condensation of each of the bis(acetyl) derivatives 8-12 and the bis(aldehyde) derivatives 30-33 with benzaldehyde and acetophenone respectively. Compounds 14, 15, 35 and 36 were alternatively obtained in 32-44 percent yields by alkylation of each of the 4-cinnamoylphenol 23 and 4-benzoylvinylphenol 38 with the appropriate dibromoalkane.
