889134-41-2

Upstream product

• 58755-70-7 1-iodo-4-methoxy-2-nitrobenzene 
• 53560-33-1 3,4,5-trimethoxyphenylacetylene 
• 889134-71-8 1,2,3-trimethoxy-5-(2-(4-methoxy-2-nitrophenyl)ethynyl)benzene 
• 889134-74-1 5-methoxy-2-(2-(3,4,5-trimethoxyphenyl)ethynyl)amine 
• 889134-30-9 (6-methoxy-1H-indazol-3-yl)-(3,4,5-trimethoxyphenyl)methanone 

Downstream Products

• 932746-72-0 2-(3-(6-methoxy-3-(3,4,5-trimethoxybenzoyl)-1H-indazol-7-yl)prop-2-ynyl)isoindoline-1,3-dione 
• 932746-65-1 [7-(4-hydroxy-but-1-ynyl)-6-methoxy-1H-indazol-3-yl]-(3,4,5-trimethoxy-phenyl)-methanone 
• 889134-75-2 C₂₆H₂₉N₃O₇ 
• 889134-61-6 C₂₆H₂₂N₂O₆ 
• 889134-59-2 C₂₅H₂₁N₃O₅ 
• 889134-58-1 C₂₂H₂₂N₂O₆ 
• 932746-71-9 (Z)-(7-(3-tert-butyldimethylsilanyloxyprop-1-enyl)-6-methoxy-1H-indazol-3-yl)(3,4,5-trimethoxyphenyl)methanone 
• 889134-62-7 (7-ethynyl-6-methoxy-1H-indazol-3-yl)-(3,4,5-trimethoxy-phenyl)-methanone 
• 889134-42-3 TH₃₃₇ 
• 932746-70-8 (7-(3-tert-butyldimethylsilanyloxyprop-1-ynyl)-6-methoxy-1H-indazol-3-yl)(3,4,5-trimethoxyphenyl)methanone 
• 889134-77-4 ((6-methoxy-7-trimethylsilylethynyl)-1H-indazol-3-yl)(3,4,5-trimethoxyphenyl)methanone 
• 889134-60-5 aroylindazole A 
• 889134-53-6 [7-(3-hydroxy-3-methyl-but-1-ynyl)-6-methoxy-1H-indazol-3-yl]-(3,4,5-trimethoxy-phenyl)-methanone 

Relevant academic research and scientific papers

Potent antitubulin tumor cell cytotoxins based on 3-aroyl indazoles

A series of 3-aroyl indazoles was synthesized. Modification of the C-7 position resulted in a significant structure-activity relationship (SAR) with acetylene modifications conferring unusual potency in a tumor cell cytotoxicity assay. The most potent com