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Upstream product

• 53560-33-1 3,4,5-trimethoxyphenylacetylene 
• 58755-70-7 1-iodo-4-methoxy-2-nitrobenzene 
• 889134-30-9 (6-methoxy-1H-indazol-3-yl)-(3,4,5-trimethoxyphenyl)methanone 
• 889134-71-8 1,2,3-trimethoxy-5-(2-(4-methoxy-2-nitrophenyl)ethynyl)benzene 
• 889134-74-1 5-methoxy-2-(2-(3,4,5-trimethoxyphenyl)ethynyl)amine 
• 889134-41-2 (7-iodo-6-methoxy-1H-indazol-3-yl)(3,4,5-trimethoxyphenyl)methanone 
• 7223-50-9 N-propargylphthalimide 

Relevant academic research and scientific papers

Potent antitubulin tumor cell cytotoxins based on 3-aroyl indazoles

A series of 3-aroyl indazoles was synthesized. Modification of the C-7 position resulted in a significant structure-activity relationship (SAR) with acetylene modifications conferring unusual potency in a tumor cell cytotoxicity assay. The most potent com